Huang Xiaolan, Du Zhihua, Cheng Jie, Cheng Qiang
Department of Computer Science, Southern Illinois University at Carbondale, IL 62901, USA.
Bioinformation. 2013 May 25;9(9):440-2. doi: 10.6026/97320630009440. Print 2013.
A computer program written in C++ has been developed which can detect all potential H-type RNA pseudoknots within any given RNA sequence. There is no limit on the length of the input sequence. A validation run of the program using the full-length (8173 nt) genomic mRNA of simian retrovirus type-1 (SRV-1) identifies the established -1 frameshift stimulating pseudokont at the gagpro junction as the most stable pseudoknot within the genomic mRNA.
已经开发了一个用C++编写的计算机程序,它可以检测任何给定RNA序列中的所有潜在H型RNA假结。输入序列的长度没有限制。使用猿猴1型逆转录病毒(SRV-1)的全长(8173 nt)基因组mRNA对该程序进行验证运行,结果表明,在gagpro连接处已确定的-1移码刺激假结是基因组mRNA中最稳定的假结。