Whisnant J P, Melton L J, Davis P H, O'Fallon W M, Nishimaru K, Schoenberg B S
Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905.
J Clin Epidemiol. 1990;43(8):791-7. doi: 10.1016/0895-4356(90)90239-l.
During the period 1960-1972, the medical record linkage index method provided an estimated average annual age- and sex-adjusted rate for first transient ischemic attack (TIA) of 134 per 100,000 population for those age 50 years and older. The cohort method estimate was 237 per 100,000 population (95% confidence limits (CL), 165-310). The discrepancy was due to 18 cases of TIA noted at the time of patient visits in the cohort analysis that were not identified from the medical record analysis. The cohort analysis for all strokes at age 50 years and older was not significantly different from the medical record linkage analysis. Although the cohort follow-up method provided better case ascertainment in this study, current indexing procedures provide case ascertainment equal to that of the cohort method and at less cost. No trend was found to suggest that incidence rates for TIA were decreasing in the period 1955-1979, in contrast to stroke in Rochester, Minn.
在1960年至1972年期间,病历关联指数法得出,50岁及以上人群首次短暂性脑缺血发作(TIA)的年龄和性别调整后平均年发病率估计为每10万人134例。队列研究法的估计值为每10万人237例(95%置信区间(CL),165 - 310)。差异是由于队列分析中在患者就诊时记录的18例TIA病例在病历分析中未被识别。50岁及以上所有中风的队列分析与病历关联分析无显著差异。尽管在本研究中队列随访法能更好地确定病例,但当前的索引程序确定病例的能力与队列研究法相当且成本更低。与明尼苏达州罗切斯特市的中风情况不同,在1955年至1979年期间未发现TIA发病率呈下降趋势。