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明尼苏达州罗切斯特市1985 - 1989年短暂性脑缺血发作的发病率

Incidence of transient ischemic attack in Rochester, Minnesota, 1985-1989.

作者信息

Brown R D, Petty G W, O'Fallon W M, Wiebers D O, Whisnant J P

机构信息

Division of Cerebrovascular Diseases and Department of Neurology, Mayo nlinic and Mayo Foundation, Rochester, MN 55905, USA

出版信息

Stroke. 1998 Oct;29(10):2109-13. doi: 10.1161/01.str.29.10.2109.

Abstract

BACKGROUND AND PURPOSE

There is scant information available on the incidence of transient ischemic attack (TIA) in a defined population. This study defines incidence rates of first TIA and subtypes of TIA during 1985-1989 and compares the incidence to that obtained from a 1960-1972 cohort study.

METHODS

Medical records of all residents of Rochester with potential diagnosis of TIA during 1985-1989 were screened to determine whether the case met the criteria for TIA. All available data were used to determine the vascular distribution of the TIA. Average annual age- and sex-adjusted incidence rates were calculated for 1985-1989, and results were compared with incidence rates determined in a Rochester-based 1960-1972 cohort study. RESILTS: Two hundred two cases of first TIA or amaurosis fugax occurred among Rochester residents during 1985-1989. The age- and sex-adjusted incidence rate for any TIA was 68/100 000 population. Incidence of amaurosis fugax was 13/100 000; anterior circulation (cerebral) TIA, 38/100 000; and vertebrobasilar distribution TIA, 14/100 000. Rates were similar to those determined from a 1960-1972 cohort study.

CONCLUSIONS

The incidence rate of TIA is 41% that of stroke incidence. TIA incidence in Rochester, Minn, is higher than has been previously reported for other sites throughout the world. Although comparison with prior time periods is difficult because of ascertainment issues, it appears that there has been no significant change in TIA incidence since the decade of the 1960s or earlier. This suggests that the most common mechanism for TIA (atherosclerosis) has not changed in prevalence, nor have risk factors leading to this mechanism.

摘要

背景与目的

关于特定人群中短暂性脑缺血发作(TIA)的发病率,现有信息匮乏。本研究确定了1985 - 1989年首次TIA及TIA亚型的发病率,并将该发病率与1960 - 1972年队列研究所得结果进行比较。

方法

筛查了1985 - 1989年罗切斯特所有可能诊断为TIA的居民的病历,以确定该病例是否符合TIA标准。利用所有可得数据确定TIA的血管分布。计算了1985 - 1989年年龄和性别调整后的年均发病率,并将结果与基于罗切斯特的1960 - 1972年队列研究确定的发病率进行比较。结果:1985 - 1989年罗切斯特居民中发生了202例首次TIA或一过性黑矇。任何TIA的年龄和性别调整发病率为68/100 000人口。一过性黑矇的发病率为13/100 000;前循环(脑)TIA为38/100 000;椎基底动脉分布TIA为14/100 000。这些发病率与1960 - 1972年队列研究所得结果相似。

结论

TIA的发病率是中风发病率的41%。明尼苏达州罗切斯特的TIA发病率高于此前世界其他地区所报告的发病率。尽管由于确诊问题难以与先前时间段进行比较,但自20世纪60年代或更早以来,TIA发病率似乎没有显著变化。这表明TIA最常见的机制(动脉粥样硬化)在患病率上没有改变,导致该机制的危险因素也没有改变。

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