Sales Márcia Cristina, Paiva Adriana de Azevedo, de Queiroz Daiane, Araújo França Costa Renata, Lins da Cunha Maria Auxiliadora, Figueroa Pedraza Dixis
Post Graduation Program in Public Health, State University of Paraíba, Paraíba.
Nutr Hosp. 2013 May-Jun;28(3):734-40. doi: 10.3305/nh.2013.28.3.6396.
To evaluate the iron nutritional status of children from 6 to 59 months of age and its relation to vitamin A deficiency.
Cross-sectional study involving 100 children, living in nine cities in the state of Paraíba, which were selected for convenience to form two study groups: children with vitamin A deficiency (serum retinol < 0.70 μmol/L; n = 50) and children without vitamin A deficiency (serum retinol ≥ 0.70 μmol/L; n = 50). The iron nutritional status was evaluated by biochemical, haematological and hematimetric indices. The cases of subclinical infection (C-Reactive Protein ≥ 6 mg/L) were excluded.
Children with vitamin A deficiency had serum iron values statistically lower than the corresponding values in children without deficiency. The other iron nutritional status indices showed no statistical difference according to presence/absence of vitamin A deficiency.
The interaction between iron and vitamin A deficiencies was evidenced in the case of circulating iron deficiency (serum iron), suggesting failure in the transport mechanisms of the mineral in children with vitamin A deficiency.
评估6至59个月儿童的铁营养状况及其与维生素A缺乏的关系。
采用横断面研究，涉及帕拉伊巴州九个城市的100名儿童，为方便起见将其分为两个研究组：维生素A缺乏儿童（血清视黄醇<0.70 μmol/L；n = 50）和非维生素A缺乏儿童（血清视黄醇≥0.70 μmol/L；n = 50）。通过生化、血液学和血液计量学指标评估铁营养状况。排除亚临床感染病例（C反应蛋白≥6 mg/L）。
维生素A缺乏儿童的血清铁值在统计学上低于非缺乏儿童的相应值。根据维生素A缺乏与否，其他铁营养状况指标无统计学差异。
在循环铁缺乏（血清铁）的情况下，铁缺乏与维生素A缺乏之间的相互作用得到证实，这表明维生素A缺乏儿童的矿物质转运机制存在缺陷。
