Dobler Claudia C
Department of Respiratory and Environmental Epidemiology, Woolcock Institute of Medical Research, The University of Sydney.
N S W Public Health Bull. 2013 Jul;24(1):34-7. doi: 10.1071/NB12099.
A recently conducted study on tuberculosis contact investigations in six Sydney tuberculosis clinics - that together managed 59% of all tuberculosis cases in NSW from January 2000 to December 2009 - found that the prevalence of tuberculosis among contacts was comparable to other low-incidence settings. However, only 9% of contacts with latent tuberculosis infection received treatment. This paper explores the results of the study, evaluating potential missed opportunities to prevent tuberculosis among contacts, and discussing the mechanisms in decision making about treatment of latent tuberculosis infection. In particular, the paper focuses on the challenges of tuberculin skin test interpretation among contacts who have received Bacille Calmette-Guérin vaccination and who were born in countries where tuberculosis is endemic.
最近对悉尼六家结核病诊所进行的一项关于结核病接触者调查的研究发现，这些诊所在2000年1月至2009年12月期间共管理了新南威尔士州59%的结核病病例，接触者中的结核病患病率与其他低发病率地区相当。然而，只有9%的潜伏性结核感染接触者接受了治疗。本文探讨了该研究的结果，评估了在接触者中预防结核病可能错失的机会，并讨论了关于潜伏性结核感染治疗决策的机制。特别是，本文重点关注了在接种过卡介苗且出生在结核病流行国家的接触者中进行结核菌素皮肤试验解读的挑战。
