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[痴呆症住院患者的临床与流行病学研究]

[Clinical and epidemiological studies on inpatients with dementia].

作者信息

Hokezu Y, Fujimoto T, Mitsuyama Y, Osame M

机构信息

Department of Neurology, Daigo Hospital.

出版信息

Nihon Ronen Igakkai Zasshi. 1990 Mar;27(2):188-92. doi: 10.3143/geriatrics.27.188.

DOI:10.3143/geriatrics.27.188
PMID:2384992
Abstract

We have studied 97 patients with dementia who have been discharged from our hospital and 106 inpatients with dementia who have been admitted during last two years in our hospital. The diagnosis of dementia was done according to the criteria of DSM-III. Based on their clinical course, neurological signs, Hachinski's ischemic score and neuroradiological findings, we divided patients into 4 groups, [senile dementia of the Alzheimer type (SDAT), vascular dementia (VD), unclassified dementia and other dementias which includes dementia with Parkinson's disease or motor neuron disease, etc.]. Concerning 70 demented patients who died during hospitalization, the average age of onset and the duration of illness of SDAT were 80.5 years old and 4.6 years respectively and those of VD were 77.6 years old and 2.7 years respectively. The common causes of death were pneumonia (50%) and cardiac failure (24%). Recurrence of cerebral vascular accident (CVA) was also another frequent cause of death in VD. The most common behavioral problems causing admission in patients of SDAT were aimless wandering, nocturnal delirium, illusion and hallucination. In VD, nocturnal delirium, aimless wandering, violence and abnormal monologue were most common causes of admission. The important causes degrading ADL of inpatients were fracture, especially fracture of the hip joint, pneumonia, intestinal bleeding and CVA. Concerning the increase of the population of over 75 years old, it will be suggested that the care and treatment of demented patients in this age group will become a major social problem.

摘要

我们研究了97例已从我院出院的痴呆患者以及106例在过去两年中入住我院的痴呆住院患者。痴呆的诊断依据DSM - III标准进行。根据患者的临床病程、神经体征、哈金斯基缺血评分和神经放射学检查结果,我们将患者分为4组,[阿尔茨海默型老年性痴呆(SDAT)、血管性痴呆(VD)、未分类痴呆以及其他痴呆,包括帕金森病或运动神经元病等所致痴呆]。对于70例在住院期间死亡的痴呆患者,SDAT的平均发病年龄和病程分别为80.5岁和4.6年,VD的平均发病年龄和病程分别为77.6岁和2.7年。常见死亡原因是肺炎(50%)和心力衰竭(24%)。脑血管意外(CVA)复发也是VD患者常见的死亡原因。导致SDAT患者入院的最常见行为问题是无目的游荡、夜间谵妄、幻觉。在VD患者中,夜间谵妄、无目的游荡、暴力行为和异常独白是入院的最常见原因。导致住院患者日常生活活动能力下降的重要原因是骨折,尤其是髋关节骨折、肺炎、肠道出血和CVA。关于75岁以上人口的增加,有人提出该年龄组痴呆患者的护理和治疗将成为一个主要的社会问题。

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