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膀胱造瘘术在撒哈拉以南非洲地区后尿道瓣膜症治疗中的作用。

Role of vesicostomy in the management of posterior urethral valve in Sub-Saharan Africa.

作者信息

Lukong C S, Ameh E A, Mshelbwala P M, Jabo B A, Gomna A, Anumah M A, Nmadu P T, Mfuh A Y

机构信息

Division of Paediatric Surgery, Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

Division of Paediatric Surgery, Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

出版信息

J Pediatr Urol. 2014 Feb;10(1):62-6. doi: 10.1016/j.jpurol.2013.06.004. Epub 2013 Jul 11.

Abstract

OBJECTIVE

To review the role of vesicostomy in the management of posterior urethral valve (PUV), in neonates and infants, given the limitations for endoscopic treatment in this setting.

METHODS

A review of 35 patients who presented with posterior urethral valve over a 10-year period. Demographic and clinical information were prospectively recorded on a structured pro forma, and the data extracted analysed using SPSS 11.0.

RESULTS

The 35 boys were aged 3 days to 10 years (median 3 weeks). Twenty-three (65.7%) had a vesicostomy (age range 3 days-3 years, median 3 weeks). The mode of presentation was poor urinary stream 15 (65.2%), urinary retention 4 (17.4%), and renal failure 6 (26.1%). Main findings were palpable bladder 23 (100%), hydronephrosis 4 (17.4%). Abdominal ultrasound confirmed hydronephrosis and thickened bladder wall, and voiding/expressive cystourethrogram confirmed dilated posterior urethra and vesicoureteric reflux in all 23 patients. Complications following vesicostomy were stoma stenosis 1 (4.3%), bladder mucosal prolapse 1 (4.3%), perivesicostomy abscess 1 (4.3%); there was no mortality. Following vesicostomy, 10 (43.5%) patients had excision of the valves and vesicostomy closure at age 2-8 years (median 4 years). They are well, with normal renal ultrasonographic findings, bladder capacity range 115-280 ml, and normal urea, serum electrolytes, creatinine, at 3 years of follow up. Thirteen (56.5%) are still awaiting valvotomy but have remained well and with normal ultrasonographic renal findings.

CONCLUSION

Vesicostomy is a useful temporising mode of urinary diversion in neonates and infants with posterior urethral valve (in the absence of unobstructed upper tracts) when facilities for endoscopic valve ablation are not readily available.

摘要

目的

鉴于新生儿和婴儿内镜治疗存在局限性,探讨膀胱造瘘术在治疗后尿道瓣膜(PUV)中的作用。

方法

回顾10年间35例后尿道瓣膜患者的情况。前瞻性地在结构化表格上记录人口统计学和临床信息,并使用SPSS 11.0对提取的数据进行分析。

结果

35例男孩年龄为3天至10岁(中位年龄3周)。23例(65.7%)行膀胱造瘘术(年龄范围3天至3岁,中位年龄3周)。主要表现为尿流不畅15例(65.2%)、尿潴留4例(17.4%)、肾衰竭6例(26.1%)。主要检查发现可触及膀胱23例(100%)、肾积水4例(17.4%)。腹部超声证实肾积水和膀胱壁增厚,排尿/排泄性膀胱尿道造影证实所有23例患者后尿道扩张和膀胱输尿管反流。膀胱造瘘术后的并发症有造口狭窄1例(4.3%)、膀胱黏膜脱垂1例(4.3%)、膀胱造瘘口周围脓肿1例(4.3%);无死亡病例。膀胱造瘘术后,10例(43.5%)患者在2至8岁(中位年龄4岁)时进行了瓣膜切除术并关闭膀胱造瘘口。随访3年时,他们情况良好,肾脏超声检查结果正常,膀胱容量为115至280毫升,尿素、血清电解质、肌酐正常。13例(56.5%)仍在等待瓣膜切开术,但情况良好,肾脏超声检查结果正常。

结论

当缺乏内镜瓣膜消融设备时,对于患有后尿道瓣膜(上尿路无梗阻)的新生儿和婴儿,膀胱造瘘术是一种有用的临时尿液转流方式。

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