Unité Biologie Moléculaire du Gène chez les Extrêmophiles, Département de Microbiologie, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris, France.
Curr Opin Virol. 2013 Oct;3(5):578-86. doi: 10.1016/j.coviro.2013.06.010. Epub 2013 Jul 10.
Viruses with single-stranded (ss) DNA genomes infect hosts from all three domains of life and are present in all imaginable environments. Many new ssDNA viruses have been recently isolated, including those infecting algae, fungi, insects and even archaea. In parallel, culture-independent metagenomic approaches have illuminated the tremendous genetic diversity of these viruses, yielding valuable insights into their evolution. Here, I integrate this knowledge to propose a scenario in which certain groups of ssDNA viruses (including Geminiviridae, Circoviridae, Parvoviridae and Microviridae) have originated from plasmids via acquisition of jelly-roll capsid protein genes from ssRNA viruses. This scenario places structurally related viruses with DNA and RNA genomes into an evolutionary continuum and highlights general evolutionary trends in the virosphere.
具有单链 (ss) DNA 基因组的病毒感染来自生命三个域的宿主，并且存在于所有可以想象的环境中。最近已经分离出许多新的 ssDNA 病毒，包括感染藻类、真菌、昆虫甚至古菌的病毒。与此同时，无需培养的宏基因组方法阐明了这些病毒的巨大遗传多样性，为它们的进化提供了有价值的见解。在这里，我整合了这些知识，提出了一个假设，即某些 ssDNA 病毒群体（包括 Geminiviridae、Circoviridae、Parvoviridae 和 Microviridae）是通过从 ssRNA 病毒中获得果冻卷状衣壳蛋白基因而从质粒起源的。这种情况将具有 DNA 和 RNA 基因组的结构相关病毒置于进化连续体中，并突出了病毒圈内的一般进化趋势。
