来自某参考单位囊性纤维化患者的洋葱伯克霍尔德菌复合体分离株的克隆多样性。
Clonal diversity among Burkholderia cepacia complex isolates from cystic fibrosis patients in a reference unit.
作者信息
Barrado Laura, Martinez M Teresa, Villa Jennifer, Orellana M Ángeles, Viedma Esther, Chaves Fernando
机构信息
Servicio de Microbiología Clínica, Hospital Universitario 12 de Octubre, Madrid, Spain.
出版信息
Enferm Infecc Microbiol Clin. 2013 Dec;31(10):665-8. doi: 10.1016/j.eimc.2013.04.025. Epub 2013 Jul 11.
INTRODUCTION
The epidemiology of Burkholderia cepacia complex (Bcc) in cystic fibrosis (CF) is not widely known.
METHODS
All CF patients with Bcc between 2002 and 2011 were reviewed, and a molecular analysis of isolates was performed.
RESULTS
The prevalence of Bcc infection was 7.2% (18/250). Molecular analysis of 16 Bcc isolates showed 5 species (7 B. contaminans, 6 B. cepacia, 1 B. cenocepacia, 1 B. multivorans, and 1 B. stabilis) and 13 sequence types. There were no cases of cross-transmission.
CONCLUSION
A high diversity of Bcc species was found in infected CF patients.
引言
洋葱伯克霍尔德菌复合体（Bcc）在囊性纤维化（CF）中的流行病学情况尚不广为人知。
方法
对2002年至2011年间所有感染Bcc的CF患者进行了回顾，并对分离株进行了分子分析。
结果
Bcc感染的患病率为7.2%（18/250）。对16株Bcc分离株的分子分析显示有5个菌种（7株污染伯克霍尔德菌、6株洋葱伯克霍尔德菌、1株嗜麦芽窄食单胞菌、1株多食伯克霍尔德菌和1株稳定伯克霍尔德菌）以及13种序列类型。无交叉传播病例。
结论
在感染的CF患者中发现了高度多样的Bcc菌种。
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