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A comparative analysis of Müller glia-mediated regeneration in the vertebrate retina.脊椎动物视网膜中穆勒胶质细胞介导的再生的比较分析。
Exp Eye Res. 2014 Jun;123:121-30. doi: 10.1016/j.exer.2013.06.019. Epub 2013 Jul 9.
2
Hedgehog signaling stimulates the formation of proliferating Müller glia-derived progenitor cells in the chick retina.刺猬信号通路刺激鸡视网膜中增殖的穆勒胶质细胞衍生祖细胞的形成。
Development. 2015 Aug 1;142(15):2610-22. doi: 10.1242/dev.121616. Epub 2015 Jun 26.
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Glucocorticoid receptors in the retina, Müller glia and the formation of Müller glia-derived progenitors.视网膜、 Müller 胶质细胞中的糖皮质激素受体和 Müller 胶质细胞源性祖细胞的形成。
Development. 2014 Sep;141(17):3340-51. doi: 10.1242/dev.109835. Epub 2014 Aug 1.
4
NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina.NF-κB 信号通路调控禽类视网膜增生性 Müller 胶质细胞源性祖细胞的形成。
Development. 2020 May 22;147(10):dev183418. doi: 10.1242/dev.183418.
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Wnt/β-catenin-signaling and the formation of Müller glia-derived progenitors in the chick retina.Wnt/β-连环蛋白信号通路与鸡视网膜中穆勒胶质细胞衍生祖细胞的形成
Dev Neurobiol. 2016 Sep;76(9):983-1002. doi: 10.1002/dneu.22370. Epub 2015 Dec 30.
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Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a.Sox2通过Lin28和Ascl1a调节再生斑马鱼视网膜中穆勒胶质细胞的重编程和增殖。
Exp Eye Res. 2017 Aug;161:174-192. doi: 10.1016/j.exer.2017.05.012. Epub 2017 May 31.
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Heparin-binding EGF-like growth factor (HB-EGF) stimulates the proliferation of Müller glia-derived progenitor cells in avian and murine retinas.肝素结合表皮生长因子样生长因子（HB-EGF）刺激鸟类和小鼠视网膜中穆勒胶质细胞源性祖细胞的增殖。
Mol Cell Neurosci. 2015 Nov;69:54-64. doi: 10.1016/j.mcn.2015.10.004. Epub 2015 Oct 21.
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mTor signaling is required for the formation of proliferating Müller glia-derived progenitor cells in the chick retina.mTor信号传导是雏鸡视网膜中增殖性穆勒胶质细胞衍生祖细胞形成所必需的。
Development. 2016 Jun 1;143(11):1859-73. doi: 10.1242/dev.133215. Epub 2016 Apr 11.
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BMP- and TGFβ-signaling regulate the formation of Müller glia-derived progenitor cells in the avian retina.BMP 和 TGFβ 信号通路调节禽类视网膜 Müller 胶质细胞衍生前体细胞的形成。
Glia. 2017 Oct;65(10):1640-1655. doi: 10.1002/glia.23185. Epub 2017 Jul 13.
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Insights on the Regeneration Potential of Müller Glia in the Mammalian Retina.对哺乳动物视网膜中 Müller 胶质细胞再生潜力的见解。
Cells. 2021 Jul 31;10(8):1957. doi: 10.3390/cells10081957.
引用本文的文献
1
Analysis of the senescence secretome during zebrafish retina regeneration.斑马鱼视网膜再生过程中衰老分泌组的分析。
Front Aging. 2025 Apr 16;6:1569422. doi: 10.3389/fragi.2025.1569422. eCollection 2025.
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Microglia-Derived IL-6 Promotes Müller Glia Reprogramming and Proliferation in Zebrafish Retina Regeneration.小胶质细胞衍生的白细胞介素-6促进斑马鱼视网膜再生中的穆勒胶质细胞重编程和增殖。
Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):67. doi: 10.1167/iovs.66.4.67.
3
Gliotic Response and Reprogramming Potential of Human Müller Cell Line MIO-M1 Exposed to High Glucose and Glucose Fluctuations.人 Müller 细胞系 MIO-M1 暴露于高糖和葡萄糖波动时的胶质反应及重编程潜能
Int J Mol Sci. 2024 Nov 29;25(23):12877. doi: 10.3390/ijms252312877.
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Regulating the formation of Müller glia-derived progenitor cells in the retina.调控视网膜中穆勒胶质细胞衍生祖细胞的形成。
Glia. 2025 Jan;73(1):4-24. doi: 10.1002/glia.24635. Epub 2024 Oct 24.
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Neuroinflammation as a cause of differential Müller cell regenerative responses to retinal injury.神经炎症作为 Müller 细胞对视网膜损伤产生不同再生反应的一个原因。
Sci Adv. 2024 Oct 4;10(40):eadp7916. doi: 10.1126/sciadv.adp7916. Epub 2024 Oct 2.
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Damage-Induced Senescent Immune Cells Regulate Regeneration of the Zebrafish Retina.损伤诱导的衰老免疫细胞调控斑马鱼视网膜再生
Aging Biol. 2024;2. doi: 10.59368/agingbio.20240021. Epub 2024 Feb 13.
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ID factors regulate the ability of Müller glia to become proliferating neurogenic progenitor-like cells.ID 因子调节 Müller 胶质细胞成为增殖性神经源性祖细胞样细胞的能力。
Glia. 2024 Jul;72(7):1236-1258. doi: 10.1002/glia.24523. Epub 2024 Mar 21.
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Cell cycle-dependent activation of proneural transcription factor expression and reactive gliosis in rat Müller glia.细胞周期依赖性激活神经前体细胞转录因子表达和反应性胶质增生在大鼠 Muller 胶质细胞中。
Sci Rep. 2023 Dec 19;13(1):22712. doi: 10.1038/s41598-023-50222-0.
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Heparin-binding epidermal growth factor and fibroblast growth factor 2 rescue Müller glia-derived progenitor cell formation in microglia- and macrophage-ablated chick retinas.肝素结合表皮生长因子和成纤维细胞生长因子 2 挽救了小胶质细胞和巨噬细胞耗竭的鸡视网膜中 Müller 胶质细胞源性祖细胞的形成。
Development. 2023 Dec 1;150(23). doi: 10.1242/dev.202070. Epub 2023 Dec 6.
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Characterization of Macroglia Response during Tissue Repair in a Laser-Induced Model of Retinal Degeneration.激光诱导视网膜变性模型中组织修复期间的大胶质细胞反应特征。
Int J Mol Sci. 2023 May 24;24(11):9172. doi: 10.3390/ijms24119172.
本文引用的文献
1
ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors.ASCL1 将小鼠 Muller 胶质细胞重编程为神经发生性视网膜祖细胞。
Development. 2013 Jun;140(12):2619-31. doi: 10.1242/dev.091355. Epub 2013 May 1.
2
New functions of Müller cells.Müller 细胞的新功能。
Glia. 2013 May;61(5):651-78. doi: 10.1002/glia.22477. Epub 2013 Feb 26.
3
Repair of the degenerate retina by photoreceptor transplantation.通过光感受器移植修复退化的视网膜。
Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):354-9. doi: 10.1073/pnas.1212677110. Epub 2012 Dec 17.
4
Wnt signaling promotes Müller cell proliferation and survival after injury.Wnt 信号通路促进损伤后 Müller 细胞的增殖和存活。
Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):444-53. doi: 10.1167/iovs.12-10774.
5
Lens and retina regeneration: new perspectives from model organisms.晶状体和视网膜再生：模型生物的新视角。
Biochem J. 2012 Nov 1;447(3):321-34. doi: 10.1042/BJ20120813.
6
Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina.Insmla 介导的基因抑制对于损伤视网膜中 Müller 胶质细胞衍生祖细胞的形成和分化是必不可少的。
Nat Cell Biol. 2012 Oct;14(10):1013-23. doi: 10.1038/ncb2586. Epub 2012 Sep 23.
7
The reactivity, distribution and abundance of Non-astrocytic Inner Retinal Glial (NIRG) cells are regulated by microglia, acute damage, and IGF1.非星形细胞内视网膜胶质细胞（NIRG）的反应性、分布和丰度受小胶质细胞、急性损伤和 IGF1 的调节。
PLoS One. 2012;7(9):e44477. doi: 10.1371/journal.pone.0044477. Epub 2012 Sep 4.
8
β-catenin/Wnt signaling controls progenitor fate in the developing and regenerating zebrafish retina.β-连环蛋白/Wnt 信号通路控制斑马鱼发育和再生视网膜祖细胞的命运。
Neural Dev. 2012 Aug 24;7:30. doi: 10.1186/1749-8104-7-30.
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Stat3 defines three populations of Müller glia and is required for initiating maximal müller glia proliferation in the regenerating zebrafish retina.Stat3 定义了 Müller 胶质细胞的三个群体，并且在再生斑马鱼视网膜中起始最大程度的 Müller 胶质细胞增殖是必需的。
J Comp Neurol. 2012 Dec 15;520(18):4294-311. doi: 10.1002/cne.23213.
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The combination of IGF1 and FGF2 and the induction of excessive ocular growth and extreme myopia.IGF1 和 FGF2 的联合作用导致眼轴过度生长和高度近视。
Exp Eye Res. 2012 Jun;99:1-16. doi: 10.1016/j.exer.2012.03.019.
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