Department of Zoology, Miami University, Oxford, OH 45056, USA.
Biochem J. 2012 Nov 1;447(3):321-34. doi: 10.1042/BJ20120813.
Comparative studies of lens and retina regeneration have been conducted within a wide variety of animals over the last 100 years. Although amphibians, fish, birds and mammals have all been noted to possess lens- or retina-regenerative properties at specific developmental stages, lens or retina regeneration in adult animals is limited to lower vertebrates. The present review covers the newest perspectives on lens and retina regeneration from these different model organisms with a focus on future trends in regeneration research.
在过去的 100 年中,在各种动物中进行了晶状体和视网膜再生的比较研究。虽然已经注意到两栖动物、鱼类、鸟类和哺乳动物在特定的发育阶段都具有晶状体或视网膜再生的特性,但成年动物的晶状体或视网膜再生仅限于较低等的脊椎动物。本综述涵盖了来自这些不同模式生物的晶状体和视网膜再生的最新观点,并重点介绍了再生研究的未来趋势。