Eguaras M G, Luque I, Montero A, García M A, Calleja F, Román M, Concha M, Ocerín J M
Service of Cardiovascular Surgery, Hospital Reina Sofia, University of Cordoba, Spain.
J Thorac Cardiovasc Surg. 1990 Aug;100(2):161-6.
From January 1978 to December 1987 we operated on 135 patients with calcified mitral stenosis. In 60 patients a conservative operation was performed (group I). Nine patients required mitral annuloplasty associated with the commissurotomy. The other 75 patients underwent mitral valve replacement (group II). In 37 patients a mechanical prosthesis was used and in 38 a biologic one. The patients given mitral valve replacement had a more heavily calcified valve than those undergoing a conservative procedure. Twenty-one patients (12 from group I and 13 from group II) required associated tricuspid annuloplasty. The mean follow-up time was 69.1 months (1 months to 10 years). There were no significant differences between the two groups in terms of operative death (0% and 4%, respectively), postoperative functional class, actuarial survival rate at 10 years (84% and 96%, respectively), and probability of freedom from thromboemboli at 10 years (98% and 96%, respectively). However, the probability of freedom from reoperation at 10 years significantly favored the conservative surgery group (84% and 69%, respectively, p less than 0.01). Finally, the probability of freedom from complications at 10 years was also significantly higher in the conservative surgery group (82% and 64%, respectively, p less than 0.005). Because of these results we believe that conservative surgery is, at present, a better alternative than mitral valve replacement for patients with partially calcified mitral stenosis.
1978年1月至1987年12月,我们对135例二尖瓣狭窄钙化患者进行了手术。60例患者接受了保守手术(第一组)。9例患者在二尖瓣交界切开术的同时需要进行二尖瓣环成形术。另外75例患者接受了二尖瓣置换术(第二组)。37例患者使用了机械瓣膜,38例使用了生物瓣膜。接受二尖瓣置换术的患者瓣膜钙化程度比接受保守手术的患者更严重。21例患者(第一组12例,第二组13例)需要同时进行三尖瓣环成形术。平均随访时间为69.1个月(1个月至10年)。两组在手术死亡率(分别为0%和4%)、术后心功能分级、10年实际生存率(分别为84%和96%)以及10年无血栓栓塞发生率(分别为98%和96%)方面无显著差异。然而,10年再次手术率方面,保守手术组明显更优(分别为84%和69%,p<0.01)。最后,保守手术组10年无并发症发生率也显著更高(分别为82%和64%,p<0.005)。基于这些结果,我们认为对于部分钙化的二尖瓣狭窄患者,目前保守手术是比二尖瓣置换术更好的选择。