Suppr超能文献

保留后叶的二尖瓣置换术的长期结果

Long term results of mitral valve replacement with preservation of the posterior leaflet.

作者信息

Katircioglu F, Yamak B, Battaloglu B, Saritas A, Kiziltepe U, Kural T, Tasdemir O, Bayazit K

机构信息

Department of Cardiovascular Surgery, Türkiye Yüksek Ihtisas Hospital of Ankara, Turkey.

出版信息

J Heart Valve Dis. 1996 May;5(3):302-6.

PMID:8793680
Abstract

BACKGROUND AND AIMS OF THE STUDY

It is commonly held that preservation of the annulo-ventricular continuity during mitral valve replacement has a beneficial effect on postoperative ventricular function. This paper presents our eight-year experience with this technique.

MATERIALS AND METHODS

From 1986 to December 1992, 120 patients with rheumatic valve disease underwent mitral valve replacement (MVR) combined with preservation of the posterior leaflet of the mitral valve. The mean age was 33.87 years (range 16 to 63). The preoperative New York Heart Association (NYHA) class was III in 64% of the patients and IV in 3%. The early (30 day) mortality rate was 2.5% (3/120). Follow up was 100% complete. The total cumulative follow up was 477 patient-years (pty) with a mean 3.94 years (range: 2-8 years).

RESULTS

The actuarial survival rate (including hospital mortality) was 87.6% at eight years. Advanced age (p = 0.0457), increased preoperative functional capacity (p = 0.0251), increased preoperative end-systolic diameter (p = 0.0352) and combined tricuspid reconstruction (p = 0.0001) were found to be independent parameters for a lower actuarial survival rate. Six patients (1.25%/pty) developed thromboembolic complications. Two of these were cerebrovascular accidents (0.41%/pty) and four were caused by mechanical valve thrombosis (1.83%/pty). Freedom from thromboembolic complications (including mechanical valve thrombosis) was 89.8% +/- 7.9%. Fifteen patients (3.14%/pty) developed valve failure, four (0.83%/pty) mechanical valve thrombosis and nine (1.88%/pty) bioprosthetic valve failure. Freedom from reoperation was 60.7% +/- 16.1%. One patient with a St. Jude Medical valve (0.2%/pty) suffered from prosthetic valve endocarditis. Three patients (0.62%/pty) died during the follow up period, and, freedom from all valve related complications was 51.4% +/- 16.1% at eight years.

CONCLUSION

Preservation of the posterior leaflet during mitral valve replacement reduces the risk of early mortality and did not cause additional complications to the patients. Despite the beneficial effects of this technique in the long term this technique did not increase the long term survival in patients with associated impaired valvular and/or ventricular function.

摘要

研究背景与目的

人们普遍认为,二尖瓣置换术中保留房室连续性对术后心室功能有有益影响。本文介绍了我们应用该技术八年的经验。

材料与方法

1986年至1992年12月,120例风湿性瓣膜病患者接受了二尖瓣置换术(MVR)并保留二尖瓣后叶。平均年龄为33.87岁(范围16至63岁)。64%的患者术前纽约心脏协会(NYHA)心功能分级为III级,3%为IV级。早期(30天)死亡率为2.5%(3/120)。随访率为100%。总累积随访时间为477患者年(pty),平均3.94年(范围:2至8年)。

结果

八年时的精算生存率(包括住院死亡率)为87.6%。高龄(p = 0.0457)、术前功能能力增加(p = 0.0251)、术前收缩末期直径增加(p = 0.0352)和联合三尖瓣重建(p = 0.0001)被发现是精算生存率较低的独立参数。6例患者(1.25%/pty)发生血栓栓塞并发症。其中2例为脑血管意外(0.41%/pty),4例由机械瓣膜血栓形成引起(1.83%/pty)。无血栓栓塞并发症(包括机械瓣膜血栓形成)的发生率为89.8%±7.9%。15例患者(3.14%/pty)发生瓣膜功能衰竭,4例(0.83%/pty)机械瓣膜血栓形成,9例(1.88%/pty)生物瓣膜功能衰竭。再次手术的发生率为60.7%±16.1%。1例植入圣犹达医疗瓣膜的患者(0.2%/pty)发生人工瓣膜心内膜炎。3例患者(0.62%/pty)在随访期间死亡,八年时无所有瓣膜相关并发症的发生率为51.4%±16.1%。

结论

二尖瓣置换术中保留后叶可降低早期死亡率风险,且未给患者带来额外并发症。尽管该技术在长期有有益效果,但在伴有瓣膜和/或心室功能受损的患者中,该技术并未提高长期生存率。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验