IEEE Trans Biomed Circuits Syst. 2011 Apr;5(2):189-96. doi: 10.1109/TBCAS.2010.2089793.
In this paper, we study the effect of temperature on the operation and performance of a xerogel-based sensor microarrays coupled to a complementary metal-oxide semiconductor (CMOS) imager integrated circuit (IC) that images the photoluminescence response from the sensor microarray. The CMOS imager uses a 32 × 32 (1024 elements) array of active pixel sensors and each pixel includes a high-gain phototransistor to convert the detected optical signals into electrical currents. A correlated double sampling circuit and pixel address/digital control/signal integration circuit are also implemented on-chip. The CMOS imager data are read out as a serial coded signal. The sensor system uses a light-emitting diode to excite target analyte responsive organometallic luminophores doped within discrete xerogel-based sensor elements. As a proto type, we developed a 3 × 3 (9 elements) array of oxygen (O2) sensors. Each group of three sensor elements in the array (arranged in a column) is designed to provide a different and specific sensitivity to the target gaseous O2 concentration. This property of multiple sensitivities is achieved by using a mix of two O2 sensitive luminophores in each pin-printed xerogel sensor element. The CMOS imager is designed to be low noise and consumes a static power of 320.4 μW and an average dynamic power of 624.6 μW when operating at 100-Hz sampling frequency and 1.8-V dc power supply.
在本文中，我们研究了温度对基于气凝胶的传感器微阵列与互补金属氧化物半导体（CMOS）成像集成电路（IC）耦合的操作和性能的影响，该 CMOS 成像集成电路（IC）对传感器微阵列的光致发光响应进行成像。CMOS 成像仪使用 32×32（1024 个元件）的有源像素传感器阵列，每个像素都包括一个高增益光电晶体管，将检测到的光信号转换为电流。还在芯片上实现了相关双采样电路和像素地址/数字控制/信号集成电路。CMOS 成像仪数据以串行编码信号读出。传感器系统使用发光二极管来激发掺杂在离散气凝胶传感器元件中的目标分析物响应的有机金属发光体。作为原型，我们开发了一个 3×3（9 个元件）的氧气（O2）传感器阵列。该阵列中每列的三个传感器元件（成组排列）旨在为目标气态 O2 浓度提供不同的特定灵敏度。这种多灵敏度特性是通过在每个引脚印刷气凝胶传感器元件中使用两种 O2 敏感发光体的混合物来实现的。CMOS 成像仪的设计具有低噪声特性，在 100-Hz 采样频率和 1.8-V 直流电源下工作时，静态功耗为 320.4 μW，平均动态功耗为 624.6 μW。
