Department of Family Medicine, University of Alberta, 205 College Plaza, Edmonton, AB T6G 2C8.
Can Fam Physician. 2013 Jul;59(7):731-6.
To summarize and determine the appropriate use for the new and old management tools for genital warts.
The following databases were searched: MEDLINE, PubMed, EMBASE, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, ACP Journal Club, and Trip. The bibliographies of retrieved papers were also reviewed. Clinical trials, qualitative review articles, consensus reports, and clinical practice guidelines were retrieved.
Symptomatic warts are prevalent in at least 1% of the population between the ages of 15 and 49, with estimates of up to 50% of the population being infected with human papillomavirus at some point in their lifetime. Imiquimod and podophyllotoxin are 2 new treatments for external genital warts that are less painful and can be applied by patients at home. In addition, the quadrivalent human papillomavirus vaccine has been shown to be efficacious in preventing genital warts and cervical cancer. There is still a role for the older treatment methods in certain situations, such as intravaginal, urethral, anal, or recalcitrant warts; or for pregnant patients.
The new treatments of external genital warts can reduce the pain of treatment and the number of office visits. Other treatment methods are still useful in certain situations.
总结和确定生殖器疣新旧管理工具的适当用途。
检索了以下数据库：MEDLINE、PubMed、EMBASE、Cochrane 系统评价数据库、Cochrane 对照试验中心注册、ACP 期刊俱乐部和 Trip。还查阅了检索到的论文的参考文献。检索了临床试验、定性综述文章、共识报告和临床实践指南。
15 至 49 岁人群中，至少有 1%的人患有症状性疣，估计一生中至少有 50%的人感染人乳头瘤病毒。咪喹莫特和鬼臼毒素是治疗外生殖器疣的 2 种新方法，它们的疼痛程度较低，患者可以在家中自行使用。此外，四价人乳头瘤病毒疫苗已被证明能有效预防生殖器疣和宫颈癌。在某些情况下，如阴道内、尿道内、肛门内或顽固的疣；或对于孕妇，仍有必要使用旧的治疗方法。
外部生殖器疣的新治疗方法可以减轻治疗的痛苦和就诊次数。在某些情况下，其他治疗方法仍然有用。
