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居民-入侵者范式:一种用于攻击、暴力和社会压力的标准化测试。

The resident-intruder paradigm: a standardized test for aggression, violence and social stress.

作者信息

Koolhaas Jaap M, Coppens Caroline M, de Boer Sietse F, Buwalda Bauke, Meerlo Peter, Timmermans Paul J A

机构信息

Department of Behavioral Physiology, Center for Behavior and Neurosciences, University Groningen.

出版信息

J Vis Exp. 2013 Jul 4(77):e4367. doi: 10.3791/4367.

DOI:10.3791/4367
PMID:23852258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3731199/
Abstract

This video publication explains in detail the experimental protocol of the resident-intruder paradigm in rats. This test is a standardized method to measure offensive aggression and defensive behavior in a semi natural setting. The most important behavioral elements performed by the resident and the intruder are demonstrated in the video and illustrated using artistic drawings. The use of the resident intruder paradigm for acute and chronic social stress experiments is explained as well. Finally, some brief tests and criteria are presented to distinguish aggression from its more violent and pathological forms.

摘要

这段视频出版物详细解释了大鼠居留者-入侵者范式的实验方案。该测试是一种在半自然环境中测量攻击性攻击和防御行为的标准化方法。视频展示了居留者和入侵者表现出的最重要行为元素,并通过艺术绘图进行说明。还解释了将居留者-入侵者范式用于急性和慢性社会应激实验的情况。最后,介绍了一些简要测试和标准,以区分攻击行为与其更暴力和病态的形式。

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The vicious cycle towards violence: focus on the negative feedback mechanisms of brain serotonin neurotransmission.
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