HP2 Laboratory, INSERM U1042, Joseph Fourier University, Grenoble, France.
Exercise Physiology Laboratory (LPE), Lyon University, Saint-Etienne, France.
Adv Exp Med Biol. 2013;789:149-155. doi: 10.1007/978-1-4614-7411-1_21.
This study aimed to compare changes in skeletal muscle, prefrontal (PFC), and motor (MC) cortex hemodynamics during prolonged (i.e., 4-h) fatiguing whole-body exercise using multichannel near-infrared spectroscopy (NIRS). Ten subjects completed three successive 80-min cycling bouts at 45 % of their maximal power output. After the 4-h cycling, maximal voluntary contraction force of the leg was decreased by ~25 %. Muscle exhibited reproductive deoxygenation patterns during each of the three bouts, whereas intra-bout cerebral hemodynamics were different throughout the protocol. Results demonstrate that specific responses to fatiguing exercise are found between tissues but also between cortical sites involved in cycling, as shown by concomitant PFC hyperoxygenation and MC deoxygenation in the first 80 min of exercise. Further insights are needed to understand the consequences of these changes regarding the integrative control of motor output while fatigue develops over several hours.
本研究旨在使用多通道近红外光谱（NIRS）比较长时间（即 4 小时）全身疲劳运动过程中骨骼肌、前额叶（PFC）和运动（MC）皮质血液动力学的变化。10 名受试者完成了 3 次连续 80 分钟的 45%最大输出功率自行车运动。4 小时的自行车运动后，腿部的最大自主收缩力下降了约 25%。肌肉在每次三个回合中都表现出重复性的去氧模式，而回合内的大脑血液动力学在整个方案中则有所不同。结果表明，在组织之间以及参与自行车运动的皮质部位之间存在特定的疲劳运动反应，表现为在运动的前 80 分钟内，PFC 同时出现过度氧合和 MC 去氧合。需要进一步的研究来了解这些变化在数小时疲劳发展过程中对运动输出的综合控制的后果。
