Sheets Erin S, Duncan Laramie E, Bjornsson Andri S, Craighead Linda W, Craighead W Edward
Colby College.
J Clin Psychol. 2014 Jun;70(6):536-45. doi: 10.1002/jclp.22028. Epub 2013 Jul 12.
Prior investigations consistently indicate that personality pathology is a risk factor for recurrence of major depressive disorder (MDD). Lack of emipircal support, however, for the Diagnostic and Statistical Manual of Mental Disorders (DSM) Fourth Edition organization of Axis II disorders supports the investigation of empirically derived factors of personality pathology as predictors of recurrence.
A sample of 130 previously depressed emerging adults (80% female; aged 18 to 21 years) were assessed for personality disorder symptoms at baseline. Participants were then followed for 18 months to identify MDD recurrence during the first 2 years of college.
Based on a previous factor analysis of DSM personality disorder criteria, eight personality pathology factors were examined as predictors of MDD recurrence. Survival analysis indicated that factors of interpersonal hypersensitivity, antisocial conduct, and social anxiety were associated with increased risk of MDD recurrence.
These findings suggest that an empirically based approach to personality pathology organization may yield useful predictors of MDD recurrence during emerging adulthood.
先前的研究一致表明，人格病理学是重度抑郁症（MDD）复发的一个风险因素。然而，缺乏对《精神疾病诊断与统计手册》（DSM）第四版轴II障碍分类的实证支持，这支持了对人格病理学的实证衍生因素作为复发预测指标的研究。
对130名既往有抑郁发作的青年（80%为女性；年龄在18至21岁之间）进行基线时的人格障碍症状评估。然后对参与者进行18个月的随访，以确定大学头两年内MDD的复发情况。
基于先前对DSM人格障碍标准的因素分析，研究了八个人格病理学因素作为MDD复发的预测指标。生存分析表明，人际过敏、反社会行为和社交焦虑因素与MDD复发风险增加有关。
这些发现表明，基于实证的人格病理学组织方法可能会产生青年期MDD复发的有用预测指标。
