包膜警告综合征
Capsular warning syndrome.
作者信息
Nadarajan Vivek, Adesina Tolu
机构信息
Department of Stroke, National Hospital for Neurology and Neurosurgery, London, UK.
出版信息
BMJ Case Rep. 2013 Jul 12;2013:bcr2013010503. doi: 10.1136/bcr-2013-010503.
We present a case of a 72-year-old man who presented with fluctuating right-sided weakness and numbness. This was characterised by episodic sudden onset weakness with resolution of symptoms in between. His symptoms and signs were becoming persistent despite the addition of dual antiplatelet therapy. The history we describe is classical of capsular warning syndrome. The patient went on to have further definitive neuroimaging which revealed a pontine infarct, rather than the expected capsular infarct. We discuss the importance of capsular warning syndrome, the proposed pathophysiological mechanisms and different locations of infarction in previous cases of capsular warning syndrome. We also discuss the lack of consensus (within the literature) in treatment options which are used to try and prevent a completed stroke occurring in cases of capsular warning syndrome.
我们报告一例72岁男性患者，其表现为右侧肢体无力和麻木症状波动。其特点是症状突然发作，呈间歇性，发作间期症状缓解。尽管加用了双联抗血小板治疗，但其症状和体征仍持续存在。我们所描述的病史是典型的包膜警告综合征。该患者进一步接受了确定性神经影像学检查，结果显示为脑桥梗死，而非预期的包膜梗死。我们讨论了包膜警告综合征的重要性、提出的病理生理机制以及既往包膜警告综合征病例中梗死的不同部位。我们还讨论了在试图预防包膜警告综合征患者发生完全性卒中的治疗选择方面（文献中）缺乏共识的情况。
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