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包膜警告综合征——一例心房颤动与放射冠梗死病例

Capsular warning syndrome-a case of atrial fibrillation and corona radiata infarct.

作者信息

Tan Sarah En Mei, Heng Kenneth Wei Jian

机构信息

Department of Emergency Medicine, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.

出版信息

Int J Emerg Med. 2023 Sep 26;16(1):62. doi: 10.1186/s12245-023-00541-w.

Abstract

BACKGROUND

Capsular warning syndrome (CWS) is a rare clinical syndrome characterised by recurrent and transient episodes of focal neurological deficits with high risk of infarction. The exact physiological mechanism of CWS remains unclear but is most commonly believed to be a result of haemodynamic insufficiency in diseased, small penetrating vessels. There are no defined treatment guidelines or established effective therapy.

CASE PRESENTATION

We describe the case of a 65-year-old man who presented to the emergency department with recurrent episodes of dysarthria coupled with right facial droop and right-sided weakness. Symptoms recurred a total of ten times within a span of 3 h. He had new onset atrial fibrillation. An initial cerebral angiogram showed mild intracranial atherosclerotic disease with no proximal large vessel occlusion or acute infarct. Magnetic resonance imaging 1 h later demonstrated an infarct in the left corona radiata.

CONCLUSIONS

This case illustrates an uncommon etiology of CWS. We will also discuss the lack of consensus in treatment options for CWS to mitigate a complete stroke.

摘要

背景

囊状预警综合征(CWS)是一种罕见的临床综合征,其特征为局灶性神经功能缺损反复发作且短暂,梗死风险高。CWS的确切生理机制尚不清楚,但最普遍认为是病变的小穿支血管血流动力学不足所致。目前尚无明确的治疗指南或已确立的有效疗法。

病例介绍

我们描述了一名65岁男性的病例,他因构音障碍反复发作并伴有右侧面部下垂和右侧肢体无力而就诊于急诊科。症状在3小时内共复发了10次。他新发房颤。初次脑血管造影显示轻度颅内动脉粥样硬化疾病,无近端大血管闭塞或急性梗死。1小时后的磁共振成像显示左侧放射冠梗死。

结论

本病例说明了CWS一种不常见的病因。我们还将讨论在CWS治疗方案中缺乏共识以减轻完全性卒中的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922b/10521567/26840b2a2131/12245_2023_541_Fig1_HTML.jpg

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