Van Helleputte Nick, Kim Sunyoung, Kim Hyejung, Kim Jong Pal, Van Hoof Chris, Yazicioglu Refet Firat
Imec, Leuven 3001, Belgium.
IEEE Trans Biomed Circuits Syst. 2012 Dec;6(6):552-61. doi: 10.1109/TBCAS.2012.2224113.
This paper proposes a 3-channel biopotential monitoring ASIC with simultaneous electrode-tissue impedance measurements which allows real-time estimation of motion artifacts on each channel using an an external μC. The ASIC features a high performance instrumentation amplifier with fully integrated sub-Hz HPF rejecting rail-to-rail electrode-offset voltages. Each readout channel further has a programmable gain amplifier and programmable 4th order low-pass filter. Time-multiplexed 12 b SAR-ADCs are used to convert all the analog data to digital. The ASIC achieves >; 115 dB of CMRR (at 50/60 Hz), a high input impedance of >; 1 GΩ and low noise (1.3 μVrms in 100 Hz). Unlike traditional methods, the ASIC is capable of actual motion artifact suppression in the analog domain before final amplification. The complete ASIC core operates from 1.2 V with 2 V digital IOs and consumes 200 μW when all 3 channels are active.
本文提出了一种具有同步电极 - 组织阻抗测量功能的三通道生物电位监测专用集成电路(ASIC),它能够使用外部微控制器(μC)实时估计每个通道上的运动伪迹。该ASIC具有一个高性能仪表放大器,其完全集成了低于1赫兹的高通滤波器,可抑制轨到轨电极偏移电压。每个读出通道还具有一个可编程增益放大器和可编程四阶低通滤波器。时分复用12位逐次逼近寄存器模数转换器(SAR - ADC)用于将所有模拟数据转换为数字数据。该ASIC实现了大于115分贝的共模抑制比(在50/60赫兹时)、大于1吉欧的高输入阻抗以及低噪声(在100赫兹时为1.3微伏均方根值)。与传统方法不同,该ASIC能够在最终放大之前在模拟域中实际抑制运动伪迹。完整的ASIC内核工作电压为1.2伏,数字输入输出为2伏,当所有三个通道都处于活动状态时,功耗为200微瓦。