O'Brien Centre for the Health Sciences Program, University of Calgary, Alberta, Canada.
J Clin Sleep Med. 2013 Jul 15;9(7):655-60. doi: 10.5664/jcsm.2830.
To assess the validity and efficacy of using electronic health data to identify a physician diagnosis of insomnia in a population of patients referred for testing at a tertiary sleep center.
Retrospective cohort study in a tertiary sleep center in Calgary, Alberta, Canada. Cohort consisted of 1,207 patients referred for sleep diagnostic testing and/or assessment by a sleep physician. Two sleep physicians independently assigned each patient a primary sleep diagnosis. Univariate logistic regression was used to identify variables that were predictive for insomnia from online questionnaire and diagnostic testing data. Diagnostic algorithms derived from these predictors and from the Insomnia Severity Index were evaluated against physician diagnosis as a reference standard.
The combination of self-reported sleep latency > 20 minutes, total sleep time < 6.5 hours per night, the inability to fall asleep after waking, BMI < 27 kg/m(2), and Epworth Sleepiness Scale score < 9 had very high specificity (99.3%) for diagnosing insomnia; however, sensitivity was poor (11.8%). Other algorithms derived from these data had either high sensitivity or high specificity. No combination of variables yielded simultaneous high sensitivity and specificity. Likewise, the Insomnia Severity Index can be highly sensitive or highly specific at identifying insomnia, but not both.
Diagnostic algorithms derived from electronic data can provide high specificity or high sensitivity for identifying insomnia.
评估在一个接受三级睡眠中心检查的患者群体中,使用电子健康数据来识别医生对失眠的诊断的有效性和功效。
这是加拿大阿尔伯塔省卡尔加里市的一个三级睡眠中心的回顾性队列研究。队列包括 1207 名因睡眠诊断测试和/或睡眠医生评估而被转介的患者。两位睡眠医生独立为每位患者分配一个主要睡眠诊断。单变量逻辑回归用于从在线问卷和诊断测试数据中识别出对失眠有预测性的变量。从这些预测因素和失眠严重程度指数得出的诊断算法与医生诊断作为参考标准进行了评估。
自我报告的入睡潜伏期>20 分钟、总睡眠时间<每晚 6.5 小时、醒来后无法入睡、BMI<27kg/m²和 Epworth 嗜睡量表评分<9 与诊断失眠的特异性非常高(99.3%);然而,敏感性较差(11.8%)。从这些数据中得出的其他算法要么具有很高的敏感性,要么具有很高的特异性。没有任何变量组合能同时具有高敏感性和特异性。同样,失眠严重程度指数在识别失眠方面可以具有很高的敏感性或特异性,但不能同时具有。
从电子数据中得出的诊断算法可以提供高特异性或高敏感性来识别失眠。