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[强力霉素与硝呋齐特治疗艾滋病患者贝氏等孢球虫感染]

[Treatment with doxycycline and nifuroxazide of Isospora belli infection in AIDS].

作者信息

Meyohas M C, Capella F, Poirot J L, Lecomte I, Binet D, Eliaszewicz M, Frottier J

机构信息

Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris.

出版信息

Pathol Biol (Paris). 1990 Jun;38(5 ( Pt 2)):589-91.

PMID:2385457
Abstract

Isospora belli infection is the most frequent coccidiosis after cryptosporidiosis in AIDS patients. Chronic watery diarrhea is observed. Trimethoprim-sulfamethoxazole is the recommended treatment. Four AIDS patients were intolerant to this drug and were treated with doxycycline and nifuroxazide. Three patients were cured. Two patients died of other infections. The two last patients relapsed and were treated again with long term doxycycline. No relapse occurred during the following twelve months.

摘要

贝氏等孢球虫感染是艾滋病患者中仅次于隐孢子虫病的最常见球虫病。可观察到慢性水样腹泻。推荐使用甲氧苄啶-磺胺甲恶唑进行治疗。4名艾滋病患者对该药物不耐受,改用强力霉素和硝呋太尔治疗。3名患者治愈。2名患者死于其他感染。最后2名患者复发,再次接受长期强力霉素治疗。在接下来的12个月内未再复发。

相似文献

1
[Treatment with doxycycline and nifuroxazide of Isospora belli infection in AIDS].[强力霉素与硝呋齐特治疗艾滋病患者贝氏等孢球虫感染]
Pathol Biol (Paris). 1990 Jun;38(5 ( Pt 2)):589-91.
2
Clinical manifestations and therapy of Isospora belli infection in patients with the acquired immunodeficiency syndrome.获得性免疫缺陷综合征患者中贝氏等孢球虫感染的临床表现及治疗
N Engl J Med. 1986 Jul 10;315(2):87-90. doi: 10.1056/NEJM198607103150203.
3
[11 cases of isosporiasis (Isospora belli) in patients with AIDS].11例艾滋病患者的等孢球虫病(贝氏等孢球虫)
Bull Soc Pathol Exot Filiales. 1988;81(2):164-72.
4
Treatment and prophylaxis of Isospora belli infection in patients with the acquired immunodeficiency syndrome.获得性免疫缺陷综合征患者中贝氏等孢球虫感染的治疗与预防
N Engl J Med. 1989 Apr 20;320(16):1044-7. doi: 10.1056/NEJM198904203201604.
5
Cryptosporidiosis and isosporiasis in patients with AIDS.艾滋病患者的隐孢子虫病和等孢子球虫病。
Infect Dis Clin North Am. 1988 Jun;2(2):485-93.
6
[Double-blind controlled study of the efficacy of nifuroxazide versus placebo in the treatment of acute diarrhea in adults].
Gastroenterol Clin Biol. 1989 May;13(5):469-72.
7
[Enteritis caused by Isospora belli in patients with the acquired immunodeficiency syndrome. Description of 9 cases].[获得性免疫缺陷综合征患者中贝氏等孢球虫引起的肠炎。9例病例描述]
Med Clin (Barc). 1990 Jun 16;95(3):84-8.
8
[Prevalence of Cryptosporidium sp and Isospora belli in patients with acquired immunodeficiency syndrome (AIDS) in Dakar (Senegal].[达喀尔(塞内加尔)获得性免疫缺陷综合征(艾滋病)患者中隐孢子虫属和贝氏等孢球虫的患病率]
Dakar Med. 1994;39(2):121-4.
9
[Trial chemoprophylaxis of traveler's diarrhea using nifuroxazide].
Pathol Biol (Paris). 1986 Jun;34(5 Pt 2):669-71.
10
Isospora belli infection. A report of two cases in patients with AIDS.贝氏等孢球虫感染。两例艾滋病患者的报告。
Med J Aust. 1991 Aug 5;155(3):194-6. doi: 10.5694/j.1326-5377.1991.tb142194.x.

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