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[强力霉素与硝呋齐特治疗艾滋病患者贝氏等孢球虫感染]

[Treatment with doxycycline and nifuroxazide of Isospora belli infection in AIDS].

作者信息

Meyohas M C, Capella F, Poirot J L, Lecomte I, Binet D, Eliaszewicz M, Frottier J

机构信息

Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris.

出版信息

Pathol Biol (Paris). 1990 Jun;38(5 ( Pt 2)):589-91.

PMID:2385457
Abstract

Isospora belli infection is the most frequent coccidiosis after cryptosporidiosis in AIDS patients. Chronic watery diarrhea is observed. Trimethoprim-sulfamethoxazole is the recommended treatment. Four AIDS patients were intolerant to this drug and were treated with doxycycline and nifuroxazide. Three patients were cured. Two patients died of other infections. The two last patients relapsed and were treated again with long term doxycycline. No relapse occurred during the following twelve months.

摘要

贝氏等孢球虫感染是艾滋病患者中仅次于隐孢子虫病的最常见球虫病。可观察到慢性水样腹泻。推荐使用甲氧苄啶-磺胺甲恶唑进行治疗。4名艾滋病患者对该药物不耐受,改用强力霉素和硝呋太尔治疗。3名患者治愈。2名患者死于其他感染。最后2名患者复发,再次接受长期强力霉素治疗。在接下来的12个月内未再复发。

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