Deluol A M, Cenac J, Michon C, Matheron S, Coulaud J P, Savel J
Service de Parasitologie, Hôpital Claude-Bernard, Paris.
Bull Soc Pathol Exot Filiales. 1988;81(2):164-72.
The study of 11 cases of isosporiasis (Isospora belli) shows that this opportunistic coccidia, alone or with Cryptosporidium, causes severe prolonged diarrhoea which worsens the prognosis and evolution of AIDS patients. A low prevalence (0.7%) is found in subjects from tropical regions. The results of treatment are disappointing. Bactrim is the only drug found to be effective but prolonged parasitological surveillance is required to detect the frequent relapses, and assess the long-time usefulness of this drug.
对11例等孢球虫病(贝氏等孢球虫)的研究表明,这种机会性球虫单独或与隐孢子虫一起,会导致严重的长期腹泻,从而使艾滋病患者的预后和病情发展恶化。在热带地区的人群中发现其患病率较低(0.7%)。治疗结果令人失望。复方新诺明是唯一被发现有效的药物,但需要长期进行寄生虫学监测,以检测频繁的复发情况,并评估这种药物的长期有效性。