Unité d'Hygiène et Epidémiologie, Groupement Hospitalier Sud Hospices Civils de Lyon, France.
J Epidemiol Glob Health. 2012 Dec;2(4):193-8. doi: 10.1016/j.jegh.2012.10.001. Epub 2012 Nov 20.
The 3ml volume currently used as the hand hygiene (HH) measure has been explored as the pertinent dose for an indirect indicator of HH compliance. A multicenter study was conducted in order to ascertain the required dose using different products.
The average contact duration before drying was measured and compared with references. Effective hand coverage had to include the whole hand and the wrist. Two durations were chosen as points of reference: 30s, as given by guidelines, and the duration validated by the European standard EN 1500. Each product was to be tested, using standardized procedures, by three nosocomial infection prevention teams, for three different doses (3, 2 and 1.5ml).
Data from 27 products and 1706 tests were analyzed. Depending on the product, the dose needed to ensure a 30-s contact duration in 75% of tests ranging from 2ml to more than 3ml, and to ensure a contact duration exceeding the EN 1500 times in 75% of tests ranging from 1.5ml to more than 3ml. The aftermath interpretation is the following: if different products are used, the volume utilized does not give an unbiased estimation of the HH compliance. Other compliance evaluation methods remain necessary for efficient benchmarking.
目前，3 毫升的容量已被用作手部卫生（HH）措施，用于间接衡量 HH 依从性的相关剂量。为了确定使用不同产品所需的剂量，进行了一项多中心研究。
测量并比较了在干燥之前的平均接触时间。有效手部覆盖范围必须包括整个手部和手腕。选择了两个时间点作为参考：30 秒，这是指南中给出的时间，另一个是经过欧洲标准 EN 1500 验证的时间。每个产品都要按照标准化程序，由三个医院感染预防小组测试三种不同的剂量（3、2 和 1.5 毫升）。
对 27 种产品和 1706 次测试的数据进行了分析。根据产品的不同，在 75%的测试中，要确保 30 秒接触时间所需的剂量范围从 2 毫升到 3 毫升以上，要确保在 75%的测试中接触时间超过 EN 1500 倍所需的剂量范围从 1.5 毫升到 3 毫升以上。以下是后续解释：如果使用不同的产品，所使用的体积并不能公正地估计 HH 的依从性。其他依从性评估方法仍然是必要的，以便进行有效的基准测试。
