Associate Professor, Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA.
CA Cancer J Clin. 2013 Sep;63(5):295-317. doi: 10.3322/caac.21186. Epub 2013 Jul 15.
Adult cancer survivors suffer an extremely diverse and complex set of impairments, affecting virtually every organ system. Both physical and psychological impairments may contribute to a decreased health-related quality of life and should be identified throughout the care continuum. Recent evidence suggests that more cancer survivors have a reduced health-related quality of life as a result of physical impairments than due to psychological ones. Research has also demonstrated that the majority of cancer survivors will have significant impairments and that these often go undetected and/or untreated, and consequently may result in disability. Furthermore, physical disability is a leading cause of distress in this population. The scientific literature has shown that rehabilitation improves pain, function, and quality of life in cancer survivors. In fact, rehabilitation efforts can ameliorate physical (including cognitive) impairments at every stage along the course of treatment. This includes prehabilitation before cancer treatment commences and multimodal interdisciplinary rehabilitation during and after acute cancer treatment. Rehabilitation appears to be cost-effective and may reduce both direct and indirect health care costs, thereby reducing the enormous financial burden of cancer. Therefore, it is critical that survivors are screened for both psychological and physical impairments and then referred appropriately to trained rehabilitation health care professionals. This review suggests an impairment-driven cancer rehabilitation model that includes screening and treating impairments all along the care continuum in order to minimize disability and maximize quality of life.
成年癌症幸存者患有各种复杂的身体和心理障碍,几乎影响到每个器官系统。身体和心理障碍都可能导致健康相关生活质量下降,应在整个治疗过程中进行识别。最近的证据表明,由于身体障碍,更多的癌症幸存者的健康相关生活质量下降,而不是由于心理障碍。研究还表明,大多数癌症幸存者将有显著的障碍,这些障碍常常未被发现和/或未得到治疗,因此可能导致残疾。此外,身体残疾是该人群痛苦的主要原因。科学文献表明,康复可以改善癌症幸存者的疼痛、功能和生活质量。事实上,康复努力可以在治疗过程的每个阶段改善身体(包括认知)障碍。这包括癌症治疗开始前的预康复和癌症急性治疗期间和之后的多模式跨学科康复。康复似乎具有成本效益,可降低直接和间接医疗保健成本,从而减轻癌症带来的巨大经济负担。因此,对幸存者进行身体和心理障碍筛查,并将其适当转介给经过培训的康复医疗保健专业人员至关重要。这篇综述提出了一种基于障碍的癌症康复模式,包括在整个治疗过程中进行筛查和治疗障碍,以最小化残疾和最大化生活质量。