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皮肌炎中钙质沉着症治疗的最新进展。

Update on the treatment of calcinosis in dermatomyositis.

作者信息

Shinjo Samuel Katsuyuki, Souza Fernando Henrique Carlos de

机构信息

Service of Rheumatology, Hospital das Clínicas, Medical School, Universidade de São Paulo, SP, Brazil.

出版信息

Rev Bras Reumatol. 2013 Apr;53(2):211-4.

Abstract

Calcinosis is a connective tissue disorder classified into the following four types: metastatic; idiopathic; iatrogenic and dystrophic. Dystrophic calcinosis can occur, for example, in dermatomyositis, mainly in juvenile dermatomyositis, and is characterized by an abnormal deposition of calcium salts in affected skin, subcutaneous tissues, and muscles or tendons, with normal serum levels of calcium and phosphate. The treatment of calcinosis in dermatomyositis remains a challenge, with few descriptions in the literature of low scientific evidence. So far, no therapy has proved to be highly effective in the combat and resolution of that comorbidity. The present study discusses the concept of calcinosis, particularly in dermatomyositis, as well as its treatment described in the literature.

摘要

钙质沉着症是一种结缔组织疾病,分为以下四种类型:转移性;特发性;医源性和营养不良性。例如,营养不良性钙质沉着症可发生于皮肌炎,主要见于青少年皮肌炎,其特征是钙盐在受影响的皮肤、皮下组织、肌肉或肌腱中异常沉积,而血清钙和磷水平正常。皮肌炎中钙质沉着症的治疗仍然是一项挑战,文献中相关描述较少且科学证据不足。到目前为止,尚无疗法被证明在对抗和解决该合并症方面具有高度有效性。本研究讨论了钙质沉着症的概念,特别是在皮肌炎中的情况,以及文献中所描述的其治疗方法。

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