幼年皮肌炎钙质沉着症的新见解：成分与治疗研究
New insight into calcinosis of juvenile dermatomyositis: a study of composition and treatment.
作者信息
Mukamel M, Horev G, Mimouni M
机构信息
Pediatric Rheumatology Unit, the Pediatric Imaging Department, and Day Care Unit, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel.
出版信息
J Pediatr. 2001 May;138(5):763-6. doi: 10.1067/mpd.2001.112473.
Milk of calcium developed in 2 children with juvenile dermatomyositis. The fluid of the collection contained macrophages, interleukin-6, IL-1, and tumor necrosis factor. The patient who had dystrophic calcinosis had a dramatic improvement with the introduction of alendronate. These findings suggest that calcinosis of juvenile dermatomyositis may be mediated by activated macrophages and that alendronate can be an effective treatment for this condition.
两名青少年皮肌炎患儿出现了钙乳症。积液中含有巨噬细胞、白细胞介素-6、白细胞介素-1和肿瘤坏死因子。患有营养不良性钙化的患者在使用阿仑膦酸钠后有显著改善。这些发现表明青少年皮肌炎的钙化可能由活化的巨噬细胞介导，且阿仑膦酸钠可能是治疗该病症的有效药物。
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