Department of OB/GYN & Reproductive Sciences, University of Maryland Baltimore, Baltimore, MD, USA.
Exp Biol Med (Maywood). 2013 May;238(5):539-48. doi: 10.1177/1535370213489437.
Ovarian function has a great deal of functional overlap between species; antral follicles grow in response to FSH, ovulation involves proteolysis, and the steroidogenic pathway is largely the same. However, embedded in these similarities are important differences that reflect the evolutionary and natural history of species and may focus future research into these critical areas. This review compares ovarian function of rats and mice with primates, focusing on estradiol and follicle growth, steroidogenesis and rupture during the periovulatory interval, and the formation of a functional corpus luteum, drawing the conclusion that careful comparison of species yields more functional information about both than studying them in isolation.
卵巢功能在物种间具有很大的功能重叠；窦卵泡的生长对 FSH 有反应，排卵涉及蛋白水解，甾体生成途径在很大程度上是相同的。然而，在这些相似之处中存在着重要的差异，这些差异反映了物种的进化和自然历史，并可能将未来的研究集中在这些关键领域。这篇综述比较了大鼠和小鼠与灵长类动物的卵巢功能，重点是雌二醇和卵泡生长、甾体生成以及排卵前后的破裂，以及功能性黄体的形成，结论是仔细比较物种可以比单独研究它们获得更多关于两者的功能信息。
