Department of Oral Biology, Clinic of Oral Rare Diseases and Genetic Diseases, School of Stomatology, the Fourth Military Medical University, Xi'an, 710032, China.
Front Med. 2013 Sep;7(3):389-94. doi: 10.1007/s11684-013-0281-3. Epub 2013 Jul 15.
Despite the current acceleration and increasing leadership of Chinese genetics research, genetics and its clinical application have largely been imported to China from the Occident. Neither genetics nor the scientific reductionism underpinning its clinical application is integral to the traditional Chinese worldview. Given that disease concepts and their incumbent diagnoses are historically derived and culturally meaningful, we hypothesize that the cultural expectations of genetic diagnoses and medical genetics practice differ between the Occident and China. Specifically, we suggest that an undiagnosed diseases program in China will differ from the recently established Undiagnosed Diseases Program at the United States National Institutes of Health; a culturally sensitive concept will integrate traditional Chinese understanding of disease with the scientific reductionism of Occidental medicine.
尽管目前中国遗传学研究的发展速度正在加快，并且领导力也在不断增强，但遗传学及其临床应用在很大程度上是从西方引入中国的。遗传学及其临床应用所基于的科学还原论都与中国传统的世界观并不完全契合。鉴于疾病概念及其既定诊断在历史上是有渊源的，并且具有文化意义，我们假设遗传诊断和医学遗传学实践的文化期望在西方和中国之间存在差异。具体来说，我们认为中国的未确诊疾病计划将与美国国立卫生研究院最近设立的未确诊疾病计划有所不同；一个具有文化敏感性的概念将把传统的中医对疾病的理解与西方医学的科学还原论结合起来。
