Oral Medicine Division, São Lucas Hospital, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
J Appl Oral Sci. 2013;21(3):215-8. doi: 10.1590/1679-775720130001.
Granuloma gravidarum (GG) is an inflammatory lesion, which develops in the oral mucosa of pregnant women in response to chronic low-grade irritants, under the influence of hormonal factors. Objective To characterize GG clinically by means of a retrospective study of the cases of the Oral Medicine Division, São Lucas Hospital, Brazil. Material and Methods Cases of GG diagnosed between 1980 and 2012 were analyzed. Data were obtained referring to the age of the patients, lesion location, clinical features, as well as the presence of local irritants. The gestation period in which the lesion developed was also investigated. Results Forty-one cases of GG were found. The lesions developed predominantly in the third trimester of pregnancy (51.22%) and the mean age of the patients was 28 years. Most GG was found in the gingiva (73.17%), was reddish color and had a mean diameter of 1.5 cm. Local irritants were involved in 75.6% of the cases. Conclusions The hormonal conditions of pregnancy can have an impact on the oral cavity, predisposing the patient to inflammatory lesions such as GG.
妊娠性牙龈瘤（GG）是一种炎症性病变，在激素因素的影响下，孕妇的口腔黏膜对慢性低水平刺激物产生反应而发展。目的 通过对巴西圣卢卡斯医院口腔医学系病例的回顾性研究，对 GG 进行临床特征分析。材料与方法 分析了 1980 年至 2012 年间诊断为 GG 的病例。获取的数据包括患者年龄、病变位置、临床特征，以及局部刺激物的存在情况。还调查了病变发展所处的妊娠阶段。结果 发现 41 例 GG。病变主要发生在妊娠晚期（51.22%），患者的平均年龄为 28 岁。大多数 GG 发生在牙龈（73.17%），呈红色，平均直径为 1.5 厘米。75.6%的病例涉及局部刺激物。结论 妊娠的激素条件可能会对口腔产生影响，使患者易患 GG 等炎症性病变。
