慢肺活量在气道阻塞检测中的重要性。
Importance of slow vital capacity in the detection of airway obstruction.
机构信息
Portuguese Red Cross, School of Health, Lisbon, Portugal.
出版信息
J Bras Pneumol. 2013 May-Jun;39(3):317-22. doi: 10.1590/S1806-37132013000300008.
OBJECTIVE
To investigate the presence of airway obstruction by determining the FEV1/FVC and FEV1/slow vital capacity (SVC) ratios.
METHODS
This was a quantitative, retrospective cross-sectional study. The sample comprised 1,084 individuals who underwent spirometry and plethysmography in a central hospital in Lisbon, Portugal. The study sample was stratified into six groups, by pulmonary function.
RESULTS
The analysis of the FEV1/FVC ratio revealed the presence of airway obstruction in 476 individuals (43.9%), compared with 566 individuals (52.2%) for the analysis of the FEV1/SVC ratio. In the airway obstruction, airway obstruction plus lung hyperinflation, and mixed pattern groups, the difference between SVC and FVC (SVC - FVC) was statistically superior to that in the normal pulmonary function, reduced FEF, and restrictive lung disease groups. The SVC - FVC parameter showed a significant negative correlation with FEV1 (in % of the predicted value) only in the airway obstruction plus lung hyperinflation group.
CONCLUSIONS
The FEV1/SVC ratio detected the presence of airway obstruction in more individuals than did the FEV1/FVC ratio; that is, the FEV1/SVC ratio is more reliable than is the FEV1/FVC ratio in the detection of obstructive pulmonary disease.
目的
通过测定 FEV1/FVC 和 FEV1/慢肺活量（SVC）比值来确定气道阻塞的存在。
方法
这是一项定量、回顾性的横断面研究。该样本包括在葡萄牙里斯本一家中心医院接受肺量测定和体积描记法检查的 1084 名个体。根据肺功能，研究样本分为六组。
结果
与分析 FEV1/SVC 比值相比，分析 FEV1/FVC 比值显示有 476 名（43.9%）个体存在气道阻塞，而有 566 名（52.2%）个体存在气道阻塞。在气道阻塞、气道阻塞伴肺过度充气和混合模式组中，SVC 与 FVC（SVC-FVC）之间的差异在统计学上优于正常肺功能、FEF 降低和限制性肺疾病组。仅在气道阻塞伴肺过度充气组中，SVC-FVC 参数与 FEV1（以预测值的%表示）呈显著负相关。
结论
与 FEV1/FVC 比值相比，FEV1/SVC 比值检测到更多的气道阻塞个体；也就是说，在检测阻塞性肺疾病方面，FEV1/SVC 比值比 FEV1/FVC 比值更可靠。
Zotero 插件