Laboratory of Physical Chemistry and Colloid Science, Wageningen University, Dreijenplein 6, 6703, HB, Wageningen, The Netherlands.
Macromol Rapid Commun. 2013 Aug;34(16):1284-8. doi: 10.1002/marc.201300422. Epub 2013 Jul 16.
A facile method for the aqueous synthesis of monodisperse and micronmeter-sized colloids with highly carboxylated surfaces is presented. The method is applied to three different monomers, styrene, methyl methacrylate, and 2,2,2-trifluoroethyl methacrylate, and illustrate tuning of the size and monodispersity in the reactions. High surface density of carboxylic acids of up to 10 COOH nm(-2) from potentiometric titrations, is achieved through copolymerization with itaconic acid. The versatility of this system is highlighted by creating highly fluorescent and monodisperse particles that can be index matched in aqueous solution and through surface modification via the carboxylic acid groups using standard amidation chemistry.
一种简便的水相合成具有高羧基化表面的单分散微米胶体的方法。该方法应用于三种不同的单体，苯乙烯、甲基丙烯酸甲酯和 2,2,2-三氟乙基甲基丙烯酸酯，并说明了在反应中粒径和单分散性的调节。通过与马来酸共聚，通过电位滴定法达到高达 10 COOH nm(-2)的高表面羧酸密度。通过共聚形成高度荧光和单分散的粒子，这些粒子在水溶液中可以匹配折射率，并且通过羧酸基团的表面修饰，使用标准的酰胺化化学，突出了该体系的多功能性。
