Medicine Department, Laennec Hospital, Quimper; Radiology Department, Cavale Blanche University Hospital, Brest, France.
J Rheumatol. 2013 Sep;40(9):1583-9. doi: 10.3899/jrheum.121544. Epub 2013 Jul 15.
The relationship between acetabular dysplasia (HD) and hip osteoarthritis (OA) remains unclear, especially for mild forms of dysplasia. Our objectives were to estimate the prevalence of HD in a population-based sample with symptoms and to evaluate potential associations linking HD, hip OA, and hip pain.
Individuals 40 to 75 years of age with symptoms in 1 or both hips were recruited during a multiregional prevalence survey. All study participants underwent examination and radiographs. Radiographs were evaluated using Kellgren-Lawrence staging (with stages ≥ 2 indicating hip OA) and HD measures [center-edge (CE) angle, acetabular inclination angle (HTE), acetabular depth (AD), and vertical center-anterior margin angle].
We studied both hips of 842 individuals (1684 hips), among whom 203 had hip OA. Compared to left hips, right hips had significantly smaller CE angles and significantly greater AD and HTE values (p ≤ 0.001). Overall, the prevalence of HD ranged from 7.6% to 22.2% of the hips depending on the measure used. The prevalence of HD was higher in individuals with hip OA, with significant differences for abnormal HTE (19.1% vs 11.4%; p < 0.0001) and abnormal CE (11.3% vs 7.5%; p = 0.04). By logistic regression, only abnormal HTE remained associated with OA. Same-side hip pain was not statistically more common in individuals with HD after stratification on OA status (p = 0.12).
Our study confirms the relationship between OA and HD, particularly as defined based on the HTE angle.
髋臼发育不良(HD)与髋骨关节炎(OA)之间的关系仍不清楚,尤其是对于轻度发育不良的情况。我们的目的是估计有症状的人群中 HD 的患病率,并评估将 HD、髋 OA 和髋痛联系起来的潜在关联。
在一项多区域患病率调查中,招募了年龄在 40 至 75 岁之间、单侧或双侧髋关节有症状的个体。所有研究参与者都接受了检查和 X 光检查。使用 Kellgren-Lawrence 分期(分期≥2 表示髋 OA)和 HD 测量值[中心边缘(CE)角、髋臼倾斜角(HTE)、髋臼深度(AD)和垂直中心-前缘角]评估 X 光片。
我们研究了 842 名个体(1684 髋)的双侧髋关节,其中 203 名患有髋 OA。与左侧髋关节相比,右侧髋关节的 CE 角度明显较小,AD 和 HTE 值明显较大(p≤0.001)。总体而言,根据使用的测量值,HD 的患病率在 7.6%至 22.2%的髋关节之间。在髋 OA 患者中,HD 的患病率更高,异常 HTE(19.1%比 11.4%;p<0.0001)和异常 CE(11.3%比 7.5%;p=0.04)的差异有统计学意义。通过逻辑回归,只有异常 HTE 与 OA 仍然相关。在按 OA 状态分层后,HD 患者同侧髋痛并不更常见(p=0.12)。
我们的研究证实了 OA 和 HD 之间的关系,特别是基于 HTE 角的定义。