Li Fusheng, Xu Xinxi, Sun Dong, Zhao Xiuguo, Tan Shulin
Institute of Medical Equipment, Academy of Military Medicine Sciences, National Biological Protection Engineering Center, Tianjin 300161, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2013 Apr;30(2):409-14.
The research on cycle change form of the pressure and the wall shear in human upper respiratory tract can strengthen understanding of the characteristics of the airflow in the place and provide us with a scientific basis for analyzing the diffusion, transition and deposition patterns of aerosol there. In our study, we used large eddy simulation to emulate the pressure and wall shear in human upper respiratory tract in conditions of the low intensive respiratory patterns, and discussed the distributing disciplinarian of the pressure and wall shear in mouth-throat model and trachea-triple bifurcation. The results showed that the pressure gradient variation in human upper respiratory tract was mainly fastened from root of epiglottis to trachea. The minimum pressure at the interim of inspiration was a duplication of the interim of expiration, and located on the posterior wall of the glottis. The pressure gradient variation was evident on trachea and its fork. The wall shear changed with the velocity of the air flow, and its direction changed periodically with breath cycle.
对人体上呼吸道压力和壁面剪应力循环变化形式的研究，能够增强对该部位气流特性的理解，并为分析那里气溶胶的扩散、转变和沉积模式提供科学依据。在我们的研究中，我们使用大涡模拟来模拟低强度呼吸模式下人体上呼吸道的压力和壁面剪应力，并探讨了口咽模型和气管-三叉分支中压力和壁面剪应力的分布规律。结果表明，人体上呼吸道的压力梯度变化主要集中在会厌根部至气管。吸气中期的最小压力是呼气中期的两倍，且位于声门后壁。气管及其分支处的压力梯度变化明显。壁面剪应力随气流速度变化，其方向随呼吸周期周期性变化。
