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[急性肺炎和胸膜炎患儿中的肺炎链球菌血清型]

[Streptococcus pneumoniae serotypes in children with acute pneumonia and pleurisy].

作者信息

Katosova L K, Tatochenko V K, Arova A A, Keshikbaeva A A, Baturo A P, Kuznetsova T A, Levin A B

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1990 May(5):23-8.

PMID:2385999
Abstract

The study of pneumococci of different serotypes, isolated from patients with acute pneumonia and pleuritis and from healthy children was carried out. Among the pneumococcal serotypes causing pneumonia and pleuritis in children serotypes 1, 6, 19, 14 and 3 were most widely spread and constituted 62.3% of all isolated pneumococci. In young children cases of acute pneumonia and pleuritis were more often induced by serotypes 6 and 14 and in older children, by serotypes 1 and 3. In patients with uncomplicated pneumonia and pleuritis differences in the detected serotypes of pneumococci were observed, and the disease course differed in severity. Serotypes 14, 3 and 3 induced destructive processes in the lungs more often than other serotypes. Monitoring of the sensitivity of pneumococci to antibiotics showed that most of the strains retained high sensitivity to penicillin and ampicillin. In most cases the detected resistant pneumococcal strains belonged to serogroup 19.

摘要

对从急性肺炎和胸膜炎患者以及健康儿童中分离出的不同血清型肺炎球菌进行了研究。在导致儿童肺炎和胸膜炎的肺炎球菌血清型中,1、6、19、14和3型分布最为广泛,占所有分离出的肺炎球菌的62.3%。在幼儿中,急性肺炎和胸膜炎病例更常由6型和14型血清型引起,而在大龄儿童中,则由1型和3型血清型引起。在无并发症的肺炎和胸膜炎患者中,观察到检测到的肺炎球菌血清型存在差异,疾病进程的严重程度也有所不同。14、3和3型血清型比其他血清型更常引起肺部的破坏性病变。对肺炎球菌对抗生素敏感性的监测表明,大多数菌株对青霉素和氨苄西林仍保持高度敏感性。在大多数情况下,检测到的耐药肺炎球菌菌株属于19血清群。

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