[The features of Haemophilus influenza and Streptococcus pneumoniae carriage and the comparative characteristics of strains isolated from healthy children and from patients with acute and chronic respiratory infections].

The biological properties (serotypes, biotypes and adhesive activity) of 839 H.influenzae strains isolated from healthy children and from patients with acute and chronic respiratory infections, as well as the serotype composition of 739 S.pneumoniae isolated from the same groups of children, were studied. The occurrence of H.influenzae carriership among healthy children varied between 13% and 78%, decreasing among older children. In 98% of cases the respiratory tract of healthy children was colonized by noncapsular forms of H.influenzae. The isolation frequency of pneumococci in healthy children was 16%, but during the period of 2 years 45% of children were found to be the transitory carriers of this infective agent. The persistence of H.influenzae and S.pneumoniae with the same biological properties lasted for 1-4 months. Repeated infections were caused, as a rule, by bacteria with other properties. S.pneumoniae persisting in healthy children and causing a chronic bronchopulmonary process had no differences in their serological composition (19, 6, 3). At the same time in acute pneumonia, complicated by pleuritis and pneumonia destruction, pneumococci of serotypes 1, 3, 5 and 14 were more frequently isolated. H.influenzae isolated from healthy children and from patients with chronic pneumonia had little difference in the occurrence of their capsular variants, but in the biotype composition of H.influenzae isolated from chronic pneumonia patients biotype 1 occurred more frequently.