[与Fra基因缺陷型和完整型鼠疫耶尔森菌相关的腹膜巨噬细胞吞噬活性]

[The phagocytic activity of peritoneal macrophages in relation to Yersinia pestis with defective and complete Fra genes].

作者信息

Grebtsova N N, Cherniavskaia A S, Lebedeva S A, Ivanova V S

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1990 May(5):7-11.

Abstract

In vitro study of phagocytosis has shown that in guinea pigs fraction 1 is conducive to the ingestion of Y. pestis by macrophages, to survival and proliferation of Y. pestis cells in these macrophages, as well as to their specific transformation leading to their increased ingestive and bactericidal activity with respect to Y. pestis. In mice the role of fraction 1 in phagocytosis has proved to be less significant.

摘要

吞噬作用的体外研究表明，在豚鼠中，组分1有利于巨噬细胞摄取鼠疫耶尔森菌，有利于鼠疫耶尔森菌细胞在这些巨噬细胞中的存活和增殖，以及有利于它们的特异性转化，从而导致其对鼠疫耶尔森菌的摄取和杀菌活性增强。在小鼠中，组分1在吞噬作用中的作用已证明不太显著。