Management of complications associated with a first-generation endocardial defibrillation lead system for implantable cardioverter-defibrillators.

An automatic cardioverter-defibrillator could be implanted using an endocardial defibrillation lead system (consisting of a tripolar defibrillation electrode catheter in conjunction with an epicostal patch electrode) in 9 of 10 patients with sustained ventricular tachycardia or ventricular fibrillation. Six lead system complications were observed during a follow-up period of 51 +/- 36 weeks. Three catheter electrode conductor fractures occurred and manifested as oversensing and subsequent delivery of inappropriate shocks (1 patient), inability to defibrillate during electrophysiologic testing 3 months after implant (1 patient) and sudden cardiac death (1 patient). Asymptomatic patch electrode conductor fractures were detected on a routine chest roentgenogram in 2 patients. Endocardial defibrillation threshold testing performed at the time of implantation resulted in malfunction of a previously implanted permanent pacemaker pulse generator in 1 patient. Catheter and patch electrode replacement procedures were performed in 3 consenting patients under local anesthesia. Endocardial defibrillation thresholds after lead replacement were comparable to those obtained at time of initial implant. Serial clinical, roentgenographic and electrophysiologic evaluation should be included in follow-up procedures for endocardial defibrillation lead systems. Monitoring for deleterious effects of endocardial defibrillation threshold testing on previously implanted pacemaker systems should be performed at the time of implant and during follow-up. Improved lead designs are necessary for long-term use of endocardial defibrillation electrodes, but replacement procedures are feasible without thoracotomy.