Department of Clinical Radiology, Kuopio University Hospital and Kuopio University, P.O. Box 1777, 70211, Kuopio, Finland,
Neuroradiology. 2013 Oct;55(10):1221-31. doi: 10.1007/s00234-013-1234-x. Epub 2013 Jul 17.
Intracranial stents have theoretical advantages in the treatment of wide-necked intracranial aneurysms, but the usability of intracranial stents in the retreatment of recurrent intracranial aneurysms is relatively unknown. In this study, we aim to evaluate the safety and efficacy of stent-assisted embolization in the retreatment of recurrent or residual intracranial aneurysms.
Retrospective evaluation was carried out for 55 consecutive patients (17 men and 38 women; mean age 51.5 years), with 56 recurrent or residual intracranial aneurysms electively retreated with stent-assisted embolization.
The technical success rate was 91% (50/55 patients). Procedural complications were encountered with six patients (11%). Angiographic and clinical follow-up data were available for 51 patients (93%), with a mean follow-up period of 28.1 months. No rebleedings were encountered during the study period. The clinical outcome was favorable in 50 patients (91%), with a Glasgow Outcome Score of 4 (N = 14) or 5 (N = 36) at the end of the study period. Poor clinical outcome correlated with very large (>2 cm) total aneurysm size (P = 0.002), large (>10 mm) recurrent aneurysm size (P = 0.011), and occurrence of periprocedural complications (P < 0.001).
Stent-assisted coil embolization is beneficial for the retreatment of wide-necked recurrent or residual intracranial aneurysms, but stability and permanent occlusion of the recurrent aneurysm is unlikely if the aneurysm exceeds 2 cm in diameter, the recurrent diameter of the aneurysm exceeds 10 mm, or if mass effect is present with the recurrent aneurysm.
颅内支架在治疗宽颈颅内动脉瘤方面具有理论优势,但颅内支架在复发性颅内动脉瘤再治疗中的可用性尚不清楚。本研究旨在评估支架辅助栓塞治疗复发性或残留颅内动脉瘤的安全性和有效性。
对 55 例(男 17 例,女 38 例;平均年龄 51.5 岁)连续患者的 56 个复发性或残留颅内动脉瘤进行回顾性评估,这些患者均采用支架辅助栓塞术选择性再治疗。
技术成功率为 91%(50/55 例患者)。6 例患者(11%)发生了程序并发症。51 例患者(93%)获得了血管造影和临床随访数据,平均随访时间为 28.1 个月。研究期间无再出血发生。50 例患者(91%)的临床结局良好,格拉斯哥结局评分在研究期末为 4 分(N=14)或 5 分(N=36)。临床结局较差与总动脉瘤直径非常大(>2cm,P=0.002)、复发性动脉瘤直径大(>10mm,P=0.011)和围手术期并发症的发生相关(P<0.001)。
支架辅助线圈栓塞有利于治疗宽颈复发性或残留颅内动脉瘤,但如果动脉瘤直径超过 2cm、复发性动脉瘤直径超过 10mm 或复发性动脉瘤存在占位效应,则动脉瘤的稳定性和永久性闭塞不太可能。