Santillan Alejandro, Schwarz Justin, Boddu Srikanth, Gobin Y Pierre, Knopman Jared, Patsalides Athos
Division of Interventional Neuroradiology, Department of Neurosurgery, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, USA.
Interv Neuroradiol. 2019 Feb;25(1):12-20. doi: 10.1177/1591019918798144. Epub 2018 Sep 4.
This retrospective study evaluates the safety and mid-term and long-term effectiveness of stent-assisted coil embolization of anterior communicating artery (Acomm) aneurysms treated with the LVIS Jr stent.
All patients treated with the LVIS Jr stent for Acomm aneurysms between June 2015 and March 2018 were included in the analysis. Details of the procedure's periprocedural adverse events, immediate aneurysm occlusion rates, and clinical and angiographic follow-up assessment were collected.
A total of 25 patients with 25 aneurysms were included. Eighteen aneurysms were found incidentally. Seven patients presented with seven ruptured aneurysms: Six were remotely ruptured and one acutely ruptured. Twenty-four patients were treated successfully and one technical failure is reported. The parent arteries measured 1.4 mm to 2.9 mm in diameter (mean, 2.3 mm). Intraprocedural thromboembolic complications occurred in two patients (8%) and an intraoperative aneurysm rupture in one patient (4%). Immediate complete aneurysm occlusion was noted in 18 out of 25 patients (72%). Clinical follow-up ranged from three months to 36 months (mean, 15.8 months) and the imaging follow-up ranged from two to 35 months (mean, 14.2 months). Complete aneurysm occlusion was achieved in 14 out of 20 patients (70%) at last angiographic follow-up. Of the two patients with in-stent thrombosis, one patient had an acutely ruptured aneurysm and the other patient was treated with an LVIS Jr stent in a Y configuration. Neurological morbidity and mortality rate were 0%.
Complex, wide-necked Acomm aneurysms can be effectively treated with stent-assisted embolization using LVIS Jr stents.
本回顾性研究评估了使用LVIS Jr支架治疗前交通动脉(Acomm)动脉瘤的安全性、中期和长期有效性。
分析2015年6月至2018年3月期间所有使用LVIS Jr支架治疗Acomm动脉瘤的患者。收集手术围手术期不良事件、即刻动脉瘤闭塞率以及临床和血管造影随访评估的详细信息。
共纳入25例患者的25个动脉瘤。18个动脉瘤为偶然发现。7例患者出现7个破裂动脉瘤:6个为陈旧性破裂,1个为急性破裂。24例患者治疗成功,报告1例技术失败。载瘤动脉直径为1.4毫米至2.9毫米(平均2.3毫米)。2例患者(8%)发生术中血栓栓塞并发症,1例患者(4%)术中动脉瘤破裂。25例患者中有18例(72%)即刻实现动脉瘤完全闭塞。临床随访时间为3个月至36个月(平均15.8个月),影像学随访时间为2个月至35个月(平均14.2个月)。在最后一次血管造影随访时,20例患者中有14例(70%)实现动脉瘤完全闭塞。在2例支架内血栓形成的患者中,1例患者为急性破裂动脉瘤,另1例患者采用Y形配置的LVIS Jr支架进行治疗。神经功能障碍和死亡率为0%。
使用LVIS Jr支架进行支架辅助栓塞可有效治疗复杂、宽颈Acomm动脉瘤。