Grabowski Matthew, Recinos Pablo, Chen Tsulee, Prayson Richard, Vogelbaum Michael
Clin Neuropathol. 2013 Nov-Dec;32(6):515-21. doi: 10.5414/NP300640.
Calcifying pseudoneoplasms of the neuraxis (CPN), also known as fibroosseous lesions, are slow-growing lesions that can occur in a variety of regions of the central nervous system (CNS). These lesions are especially rare, with no more than 30 intracranial cases reported in the literature. Due to its non-malignant/non-metastatic course, one can expect an excellent prognosis with a successful complete resection. However, depending on the location of presentation within the CNS, CPN can present unique challenges in diagnosis and subsequently, the treatment course undertaken. We present a case of an intracranial, extra-axial CPN in a 49-year-old woman, the second to be reported in this location ever and first in 30 years, and detail the clinical, histopathologic and radiological features of a CPN along with a review of the literature.
神经轴钙化性假瘤（CPN），也称为纤维骨病变，是一种生长缓慢的病变，可发生于中枢神经系统（CNS）的多个区域。这些病变极为罕见，文献报道的颅内病例不超过30例。由于其非恶性/非转移性病程，成功完整切除后预后良好。然而，根据CPN在CNS内的发病部位，其在诊断及后续治疗过程中可能会带来独特的挑战。我们报告一例49岁女性颅内、轴外CPN病例，这是该部位第二例报道，也是30年来首例，并详细阐述CPN的临床、组织病理学和放射学特征，同时对文献进行回顾。
