Lyapichev Kirill, Bregy Amade, Shah Ashish H, Shah Kinjal, Desai Mehul B, Petito Carol, Komotar Ricardo J
Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Department of Neurological Surgery, University of Miami, Miller School of Medicine, Miami, Florida, USA.
BMJ Case Rep. 2014 Dec 5;2014:bcr2014206855. doi: 10.1136/bcr-2014-206855.
Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare and typically benign lesions that can occur anywhere within the central nervous system. Aetiology of this lesion is unclear and surgical removal is usually curative. We present a 24-year-old male patient with a history of occipital migraines who was admitted after sudden onset seizure and loss of vision. CT and MRI demonstrated a small calcifying lesion in the right temporo-occipital lobe. The patient underwent gross total resection of the tumour mass and pathological analysis revealed a CAPNON. The preoperative diagnosis of CAPNON remains difficult due to unspecific radiological findings, yet a clear understanding of characteristic pathological findings and prognosis of CAPNON remains paramount.
神经轴钙化性假瘤(CAPNON)是罕见的、通常为良性的病变,可发生于中枢神经系统的任何部位。该病变的病因尚不清楚,手术切除通常可治愈。我们报告一名24岁男性患者,有枕部偏头痛病史,因突然发作癫痫和视力丧失入院。CT和MRI显示右侧颞枕叶有一个小的钙化病变。患者接受了肿瘤块的全切除,病理分析显示为CAPNON。由于放射学表现不具特异性,CAPNON的术前诊断仍然困难,但对CAPNON特征性病理表现和预后的清晰了解仍然至关重要。