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过敏性结膜炎与希腊北部最常见的过敏原。

Allergic conjunctivitis and the most common allergens in Northern Greece.

机构信息

Laboratory of Experimental Opthalmology, Medical School, Aristotle University of Thessaloniki, University Campus, Thessaloniki 54124, Greece.

出版信息

World Allergy Organ J. 2013 Jul 16;6(1):12. doi: 10.1186/1939-4551-6-12.

Abstract

BACKGROUND

Ocular allergies affect a great part of the general population and often co exist with other allergic manifestations. In the present study, the prevalence of allergic conjunctivitis and the commonest allergens in allergic patients at an outpatient unit in Thessaloniki, Greece were evaluated.

METHODS

This is a retrospective study regarding allergic patients who referred to an outpatient clinic between the 1st of January of 1996 and the 31st of December 2010. They completed relative questionnaires concerning their allergic condition. The patients who were included in our study had allergic conjunctivitis confirmed by ophthalmologists and were divided into 4 groups. The criteria used were the existence of allergic conjunctivitis alone or with other allergic co- morbidities. The patients then underwent skin prick tests after consent according to current guidelines.

RESULTS

The archives of 1239 allergic patients were evaluated and 497 patients (40,11%) who manifested eye allergic symptoms were included in our study. 448 patients (90.14%) had allergic conjunctivitis in conjunction with asthma or rhinitis or both. 370 patients underwent skin prick tests and 284 of them (124 males-160 females) were positive for at least 1 of the 8 tested allergens (76.75%). 166 were positive to a grass mix (58.45%), 130 to olea European (45.77%), 124 to dust mites mix (43.66%), 58 to cypress (20.42%), 71 to parietaria officinalis (25.00%), 67 to cat dander (23.59%), 35 to dog dander (12.32%) and 32 to Altenaria (11.26%).

CONCLUSIONS

Symptoms of ocular allergy are very common in patients with allergic rhinitis and asthma. Men had slightly higher percentages of positive skin prick tests, except for dog dander and Altenaria. Conjunctivitis should not be overlooked as an allergic entity when evaluating allergic patients.

摘要

背景

眼部过敏影响了很大一部分普通人群,并且常常与其他过敏表现共存。在本研究中,评估了希腊塞萨洛尼基一家门诊患者的过敏性结膜炎患病率和最常见的过敏原。

方法

这是一项回顾性研究,涉及 1996 年 1 月 1 日至 2010 年 12 月 31 日期间到门诊就诊的过敏患者。他们填写了有关过敏情况的问卷。纳入本研究的患者均经眼科医生确诊为过敏性结膜炎,并分为 4 组。使用的标准是是否存在单纯性过敏性结膜炎或是否伴有其他过敏性合并症。然后,根据现行指南,在征得患者同意后进行皮肤点刺试验。

结果

评估了 1239 例过敏患者的档案,其中 497 例(40.11%)表现出眼部过敏症状,纳入本研究。448 例(90.14%)患者患有过敏性结膜炎,同时患有哮喘或鼻炎,或两者兼有。370 例患者进行了皮肤点刺试验,其中 284 例(124 名男性-160 名女性)对 8 种测试过敏原中的至少 1 种呈阳性(76.75%)。166 例对草混合物呈阳性(58.45%),130 例对欧洲橄榄呈阳性(45.77%),124 例对尘螨混合物呈阳性(43.66%),58 例对柏树呈阳性(20.42%),71 例对豚草呈阳性(25.00%),67 例对猫皮屑呈阳性(23.59%),35 例对狗皮屑呈阳性(12.32%),32 例对链格孢属呈阳性(11.26%)。

结论

过敏性鼻炎和哮喘患者的眼部过敏症状非常常见。男性的皮肤点刺试验阳性率略高,但狗皮屑和链格孢属除外。在评估过敏患者时,不应忽视结膜炎作为一种过敏实体。

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