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鼻息肉病中的鼻窦骨质改变:患病率及其与疾病严重程度的关系。

Sinonasal bony changes in nasal polyposis: prevalence and relationship to disease severity.

作者信息

Siddiqui J, Millard R, Eweiss A Z, Beale T, Lund V J

机构信息

Department of Rhinology, Royal National Throat, Nose and Ear Hospital, London, UK.

出版信息

J Laryngol Otol. 2013 Aug;127(8):755-9. doi: 10.1017/S0022215113001461. Epub 2013 Jul 18.

DOI:10.1017/S0022215113001461
PMID:23866776
Abstract

BACKGROUND

Nasal polyposis is characterised by opacification of the nasal cavities, paranasal sinuses and ostiomeatal complexes on computed tomography scanning. Sinonasal bony changes have been reported as disease sequelae.

OBJECTIVES

To assess the prevalence of sinonasal bone expansion, erosion and thickening in patients with nasal polyposis, and to correlate disease severity with the prevalence of bony changes.

METHODS

A retrospective radiological study was conducted comprising pre-operative computed tomography scans of 104 patients with nasal polyposis and scans of 44 age- and gender-matched individuals (control group) without sinonasal disease. Lund–Mackay scores and bony changes were quantified.

RESULTS

Ninety-three per cent of the study group scans showed sinonasal bony change, with no changes in the control group. Radiological severity of nasal polyposis correlated positively with the prevalence of bony changes (rs = 0.31; p < 0.01).

CONCLUSION

Sinonasal bony changes were common in the study group. This highlights the importance of pre- and intra-operative imaging, which can help to prevent intra-operative complications. As bony changes may mimic invasive disease, the importance of histological assessment of polyps is emphasised.

摘要

背景

鼻息肉病的特征是在计算机断层扫描中鼻腔、鼻窦和窦口鼻道复合体出现混浊。鼻窦骨改变已被报道为疾病后遗症。

目的

评估鼻息肉病患者鼻窦骨扩张、侵蚀和增厚的发生率,并将疾病严重程度与骨改变的发生率相关联。

方法

进行了一项回顾性放射学研究,包括104例鼻息肉病患者的术前计算机断层扫描以及44例年龄和性别匹配的无鼻窦疾病个体(对照组)的扫描。对Lund-Mackay评分和骨改变进行量化。

结果

研究组93%的扫描显示鼻窦骨改变,对照组无改变。鼻息肉病的放射学严重程度与骨改变的发生率呈正相关(rs = 0.31;p < 0.01)。

结论

鼻窦骨改变在研究组中很常见。这突出了术前和术中成像的重要性,其有助于预防术中并发症。由于骨改变可能类似侵袭性疾病,强调了息肉组织学评估的重要性。

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