Bilge Türk, Akpinar Meltem, Mahmutoğlu Abdullah Soydan, Uçak Irmak, Uslu Coşkun Berna
*ENT Clinic†Radiology Clinic, Şişli Hamidiye Etfal Training and Research Hospital, Şişli, Istanbul, Turkey.
J Craniofac Surg. 2016 Jul;27(5):1336-9. doi: 10.1097/SCS.0000000000002731.
Although sinonasal anatomic variations have been postulated as a risk factor for sinus disease, the role of anatomic abnormalities in the pathogenesis of nasal polyps is still unclear. This study was conducted to examine the association of sinonasal polyposis with anatomic variations.
The paranasal sinus computerized tomography scans of 155 patients with sinonasal polyposis were examined retrospectively from January 2012 to 2014 in a tertiary care hospital. Paranasal sinus computerized tomography of 100 patients without complaints and signs of sinus disease were also included to serve as control group. The incidence of anatomic variations was evaluated. The sinonasal polyposis and control group data was compared statistically.
The incidence of the septal deviation, concha bullosa, Agger nasi, frontal sinus hypoplasiaand accessory sinus ostium in healthy subjects, and sinonasal polyposis patients revealed statistically significant difference. The mentioned variations were found significantly higher in sinonasal polyposis patients (P = 0.000, P = 0.000, P = 0.001, P = 0.002, and P = 0.035 respectively) and may be predisposing for this pathology.
Considering the results obtained, the presence of septal deviation, concha bullosa, Agger nasi cell, frontal sinus hypoplasiaand accessory sinus ostium may play role in pathogenesis of sinonasal polyposis.
尽管鼻窦解剖变异被认为是鼻窦疾病的一个危险因素，但解剖异常在鼻息肉发病机制中的作用仍不清楚。本研究旨在探讨鼻窦息肉病与解剖变异之间的关联。
回顾性分析2012年1月至2014年在一家三级医院就诊的155例鼻窦息肉病患者的鼻窦计算机断层扫描。另外纳入100例无鼻窦疾病症状和体征的患者的鼻窦计算机断层扫描作为对照组。评估解剖变异的发生率。对鼻窦息肉病组和对照组的数据进行统计学比较。
健康受试者与鼻窦息肉病患者中鼻中隔偏曲、泡状鼻甲、鼻丘、额窦发育不全及副鼻窦口的发生率存在统计学显著差异。上述变异在鼻窦息肉病患者中明显更高（分别为P = 0.000、P = 0.000、P = 0.001、P = 0.002和P = 0.035），可能是这种病理状态的易感因素。
考虑到所获得的结果，鼻中隔偏曲、泡状鼻甲、鼻丘气房、额窦发育不全及副鼻窦口可能在鼻窦息肉病的发病机制中起作用。
