Quinn M, Deakin A H, McDonald D A, Cunningham I K T, Payne A P, Picard F
Laboratory of Human Anatomy, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
Knee. 2013 Oct;20(5):319-23. doi: 10.1016/j.knee.2013.06.008. Epub 2013 Jul 15.
Local infiltration analgesia (LIA) is a relatively novel technique developed for effective pain control following total knee arthroplasty (TKA), reducing requirements for epidural or parenteral postoperative analgesia. This study investigated the anatomical spread of an LIA used in TKA to identify the nerve structures reached by the injected fluid.
Six fresh-frozen cadaveric lower limbs were injected according to a standardised LIA technique with a solution of latex and India ink to enable visualisation. Wounds were closed and limbs placed flat in a freezer at -20°C for two weeks. Limbs were then either sliced or dissected to identify solution locations.
Solution was found from the proximal thigh to the middle of the lower leg. The main areas of concentration were the popliteal fossa, the anterior aspect of the femur and the subcutaneous tissue of the anterior aspect of the knee. There was less solution in the lower popliteal fossa. The solution was found to reach the majority of nerves, with good infiltration of nerves supplying the knee.
These results support the positive clinical outcomes with this LIA technique. However, the lack of infiltration into the lower popliteal fossa suggests more fluid or a different injection point could be used. The solution reaching the extensor muscles of the lower leg is likely to have no beneficial analgesic effect for a TKA patient. The LIA technique is already used in clinical practice following total knee arthroplasty. Results from this study show there may be scope to optimise the injection sites in LIA technique.
局部浸润镇痛(LIA)是为全膝关节置换术(TKA)后有效控制疼痛而开发的一种相对新颖的技术,可减少术后硬膜外或胃肠外镇痛的需求。本研究调查了TKA中使用的LIA的解剖学扩散情况,以确定注入液体所到达的神经结构。
按照标准化的LIA技术,向六个新鲜冷冻的尸体下肢注射乳胶和印度墨水的溶液,以便可视化。伤口闭合,肢体平放在-20°C的冰箱中两周。然后对肢体进行切片或解剖,以确定溶液的位置。
在大腿近端至小腿中部发现了溶液。主要集中区域是腘窝、股骨前部和膝关节前部的皮下组织。腘窝下部的溶液较少。发现溶液到达了大多数神经,对供应膝关节的神经有良好的浸润。
这些结果支持了这种LIA技术的积极临床效果。然而,缺乏对腘窝下部的浸润表明可以使用更多的液体或不同的注射点。到达小腿伸肌的溶液对TKA患者可能没有有益的镇痛作用。LIA技术已在全膝关节置换术后的临床实践中使用。本研究结果表明,LIA技术的注射部位可能有优化的空间。