Senaldi E, Lee M H, Toth I, Grace W
Department of Pathology, St. Vincent's Hospital and Medical Center, New York, NY 10011.
Cancer. 1990 Sep 1;66(5):960-4. doi: 10.1002/1097-0142(19900901)66:5<960::aid-cncr2820660525>3.0.co;2-3.
Hodgkin's disease (HD) after treatment of non-Hodgkin's lymphoma (NHL) has been reported but is extremely rare, and to the authors' knowledge has not been reported in patients with acquired immune deficiency syndrome (AIDS). The authors present a case of an AIDS patient who developed mixed cellularity type HD 2.5 years after chemotherapy and radiotherapy for Stage II NHL. The patient died of infectious causes 1.5 years after interferon therapy for the HD. Autopsy revealed Stage IV HD, mixed cellularity type.