School of Life Sciences and State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, China.
Food Chem. 2013 Dec 1;141(3):2385-93. doi: 10.1016/j.foodchem.2013.05.095. Epub 2013 May 29.
To fulfill the natural human needs of selenium, selenium biofortification has been carried out in rice (Oryza sativa) in recent years. Despite some improvements have been made, the increase of selenium content in rice was still limited and a large amount of fertilisers are often required, which may cause environmental pullution. In this study, we further improved the selenium biofortification of rice by using less selenium fertilisers (10.5 g selenium/hectare) whereas, largely increasing selenium content in rice grains (up to 51 times vs. control). Furthermore, selenium speciation analysis, in vitro gastrointestinal digestion and antioxidant assays were performed to evaluate the selenium bioaccessibility and bioavailability in selenium-enriched rice grains. The major selenium species found were readily absorbable selenomethionine. Meanwhile, the selenium-enriched rice grains have significantly higher antioxidant bioactivities. In conclusion, this selenium-enriched rice has enormous potential for selenium supplementation in humans.
为了满足人类对硒的自然需求，近年来已在水稻（Oryza sativa）中进行了硒的生物强化。尽管已经取得了一些进展，但大米中硒含量的增加仍然有限，而且通常需要大量的肥料，这可能会造成环境污染。在这项研究中，我们通过使用更少的硒肥料（每公顷 10.5 克硒），进一步提高了水稻的硒生物强化效果，而使大米中的硒含量大大增加（与对照相比高达 51 倍）。此外，还进行了硒形态分析、体外胃肠消化和抗氧化测定，以评估富硒大米中硒的生物可及性和生物利用度。发现的主要硒形态是易吸收的硒代蛋氨酸。同时，富硒大米具有更高的抗氧化生物活性。总之，这种富硒大米具有巨大的潜力，可以作为人类补硒的来源。
