Keck P E, Pope H G, Hudson J I, McElroy S L, Yurgelun-Todd D, Hundert E M
Biological Psychiatry Laboratory, McLean Hospital, Belmont, MA 02178.
Compr Psychiatry. 1990 Jul-Aug;31(4):275-83. doi: 10.1016/0010-440x(90)90034-p.
We administered structured diagnostic interviews and family history evaluations to 69 outpatient women meeting the new DSM-III-R criteria for bulimia nervosa. This group was compared with 50 women with DSM-III bulimia, 24 women with major depression, and 28 nonpsychiatric control women, all recruited during previous studies. On both phenomenologic and family history assessments, the women with DSM-III-R bulimia nervosa closely resembled the women with DSM-III bulimia, and both groups differed significantly from controls in their prevalence of personal and familial major mood disorders. These data support a relationship between bulimia nervosa and major mood disorders, consistent with that suggested by studies of bulimia assessed by earlier diagnostic criteria.
我们对69名符合神经性贪食症新的《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)标准的门诊女性进行了结构化诊断访谈和家族史评估。将该组与50名符合DSM-III神经性贪食症标准的女性、24名患有重度抑郁症的女性以及28名非精神科对照女性进行比较,所有这些女性均是在之前的研究中招募的。在现象学和家族史评估方面,符合DSM-III-R神经性贪食症标准的女性与符合DSM-III神经性贪食症标准的女性非常相似,并且两组在个人和家族性重度情绪障碍的患病率方面与对照组均有显著差异。这些数据支持了神经性贪食症与重度情绪障碍之间的关系,这与早期诊断标准评估的神经性贪食症研究结果一致。